Box 1. Which animals are protected under the legislation of selected countries?

Globally, legislation differs between countries and geographical regions. Either all animals used in research are protected (specific species or ages are not prescribed) or the legislation identifies which animals at what stage of development are included.

Country or regionProtected animals
Australia Vertebrates of all developmental stages
Cephalopods of all developmental stages 
Brazil All animals 
China All animals 
Europe Adult vertebrates
Mammalian, bird and reptile fetuses in last third of development
Amphibians and fish at the free-feeding stage
Cephalopods at the free-feeding stage 
India All animals 
South Africa All vertebrates including eggs, fetuses and embryos
Cephalopods
Decapods 
USA Warm-blooded vertebrates except farm animals used in food and fibre research, rats of the genus Rattus and mice of the genus Mus 
Country or regionProtected animals
Australia Vertebrates of all developmental stages
Cephalopods of all developmental stages 
Brazil All animals 
China All animals 
Europe Adult vertebrates
Mammalian, bird and reptile fetuses in last third of development
Amphibians and fish at the free-feeding stage
Cephalopods at the free-feeding stage 
India All animals 
South Africa All vertebrates including eggs, fetuses and embryos
Cephalopods
Decapods 
USA Warm-blooded vertebrates except farm animals used in food and fibre research, rats of the genus Rattus and mice of the genus Mus 
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