Table 1.

Genotype of mice resulting from Cited2 heterozygous intercross on a mixed C57BL6:129 genetic background

Genotype
StageCited2+/+Cited2+/−Cited2−/−P
8.5 dpc 68 184 100 0.0379 
9.5 dpc 36 80 29 0.3283 
10.5 dpc 36 84 31 0.3255 
11.5 dpc 30 76 28 0.2897 
12.5 dpc 14 23 10 0.7039 
13.5 dpc 13 22 10 0.8097 
14.5 dpc 106 159 85 (+6 dead) 0.0657 
15.5 dpc 14 19 8 (+5 dead) 0.3724 
16.5 dpc 12 8 (+1 dead) 0.6839 
17.5 dpc 0.6065 
PD21 402 615 <0.0001 
Genotype
StageCited2+/+Cited2+/−Cited2−/−P
8.5 dpc 68 184 100 0.0379 
9.5 dpc 36 80 29 0.3283 
10.5 dpc 36 84 31 0.3255 
11.5 dpc 30 76 28 0.2897 
12.5 dpc 14 23 10 0.7039 
13.5 dpc 13 22 10 0.8097 
14.5 dpc 106 159 85 (+6 dead) 0.0657 
15.5 dpc 14 19 8 (+5 dead) 0.3724 
16.5 dpc 12 8 (+1 dead) 0.6839 
17.5 dpc 0.6065 
PD21 402 615 <0.0001 

Ratios of genotypes were tested for goodness of fit to expected Mendelian segregation (1:2:1) by ϰ2 analysis, calculated with two degrees of freedom. P value calculated at 14.5, 15.5 and 16.5 dpc for living embryos only.

dpc, days post coitum; PD, postnatal day.

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