TSK cooperates with VG1 to induce the primitive streak formation
| Molecule . | Sample/total . | % . |
|---|---|---|
| TSKA | 0/35 | 0 |
| TSKB | 2/38 | 5 |
| VG1 | 9/40 | 23 |
| Chordin | 6/54 | 11 |
| FGF8B | 14/66 | 21 |
| Nodal | 1/44 | 2 |
| TSKA + VG1 | 21/42 | 50 |
| TSKA + chordin | 7/48 | 15 |
| TSKA + FGF8B | 12/46 | 26 |
| TSKA + Nodal | 0/44 | 0 |
| TSKB + VG1 | 37/76 | 49 |
| TSKB + chordin | 6/44 | 14 |
| TSKB + FGF8B | 12/48 | 25 |
| TSKB + Nodal | 2/53 | 4 |
| VG1 + chordin | 22/44 | 50 |
| VG1 + Nodal | 17/43 | 40 |
| TSKA + VG1 + chordin | 39/51 | 76 |
| TSKB + VG1 + chordin | 25/32 | 78 |
| Molecule . | Sample/total . | % . |
|---|---|---|
| TSKA | 0/35 | 0 |
| TSKB | 2/38 | 5 |
| VG1 | 9/40 | 23 |
| Chordin | 6/54 | 11 |
| FGF8B | 14/66 | 21 |
| Nodal | 1/44 | 2 |
| TSKA + VG1 | 21/42 | 50 |
| TSKA + chordin | 7/48 | 15 |
| TSKA + FGF8B | 12/46 | 26 |
| TSKA + Nodal | 0/44 | 0 |
| TSKB + VG1 | 37/76 | 49 |
| TSKB + chordin | 6/44 | 14 |
| TSKB + FGF8B | 12/48 | 25 |
| TSKB + Nodal | 2/53 | 4 |
| VG1 + chordin | 22/44 | 50 |
| VG1 + Nodal | 17/43 | 40 |
| TSKA + VG1 + chordin | 39/51 | 76 |
| TSKB + VG1 + chordin | 25/32 | 78 |
A pellet of VG1 was grafted into lateral margin of pre-streak stage embryo;6 hours later, a pellet of cells expressing above molecule was implanted in some combinations.