Effects of misexpression of TSK and VG1 in the area pellucida
Molecule
.
Sample/total
.
%
.
TSKA
0/8
0
TSKB
0/10
0
VG1
6/28
21
VG1 + WNT1
9/14
64
TSKA + VG1
18/30
60
TSKB + VG1
23/46
50
TSKA + VG1 + WNT1
26/30
87
TSKB + VG1 + WNT1
25/29
86
Molecule
.
Sample/total
.
%
.
TSKA
0/8
0
TSKB
0/10
0
VG1
6/28
21
VG1 + WNT1
9/14
64
TSKA + VG1
18/30
60
TSKB + VG1
23/46
50
TSKA + VG1 + WNT1
26/30
87
TSKB + VG1 + WNT1
25/29
86
A pellet of cells expressing above molecule was grafted into the area pellucida of pre-streak stage XII embryos; 24 hours later, the ectopic induction of brachyury, a marker for primitive streak, was examined by in situ hybridization.