Summary of differences in enzyme specific activities in tissues of Fundulus grandis held under normal and reduced oxygen levels for 4 weeks at 27°C
| . | . | Pathway . | . |
|---|---|---|---|
| . | Glycolysis . | Glycogen metabolism . | Gluconeogenesis . |
| Tissue | |||
| Muscle | ↓ PGI, ALD, PYK, LDH | ↓ GPase (Total) | n.d. |
| Liver | ↑ PFK, GAPDH, PGK, LDH | none | ↑ MDH, FBPase |
| Heart | ↑ HK | n.d. | n.d. |
| Brain | ↑ HK | n.d. | n.d. |
| . | . | Pathway . | . |
|---|---|---|---|
| . | Glycolysis . | Glycogen metabolism . | Gluconeogenesis . |
| Tissue | |||
| Muscle | ↓ PGI, ALD, PYK, LDH | ↓ GPase (Total) | n.d. |
| Liver | ↑ PFK, GAPDH, PGK, LDH | none | ↑ MDH, FBPase |
| Heart | ↑ HK | n.d. | n.d. |
| Brain | ↑ HK | n.d. | n.d. |
PGI, phosphoglucoisomerase; ALD, aldolase; PYK, pyruvate kinase; LDH,lactate dehydrogenase; PFK, phosphofructokinase; GAPDH,glyceraldehyde-3-phosphate dehydrogenase; PGK, phosphoglycerokinase; MDH,malate dehydrogenase; FBPase, fructose-1,6-bisphosphatase; HK, hexokinase.
The enzymes shown are those that were significantly different between treatment groups at P≤0.001. n.d. not determined.
↑ Higher in hypoxia than in normoxia; ↓ Lower in hypoxia than in normoxia.