Percentages of apoptotic GW and NB2-4t motoneurons in various genetic backgrounds
| GW . | WT . | Ubx1 . | en>Ubx . | hs-Ubx (3.5 hours AEL) . | hs-Ubx (12 hours AEL) . | AntpW10 . | en>Antp . | Ubx1/+ . | AntpW10,Ubx1/+ . | AntpW10,Ubx1/AntpW10 . | AntpW10,Ubx1 . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| T1-T2 | 0 | 0 | 80 | 0 | 21.9 | 35 | 0 | 0 | 2.8 | ND | ND |
| (n=55) | (n=28) | (n=20) | (n=27) | (n=64) | (n=20) | (n=28) | (n=28) | (n=36) | |||
| T3 | 55.6 | 0 | 90 | 100 | 90.6 | 90 | 30.8 | 7.1 | 16.7 | 36.4 | 23.5 |
| (n=27) | (n=14) | (n=10) | (n=12) | (n=32) | (n=10) | (n=13) | (n=14) | (n=18) | (n=22) | (n=17) | |
| A1-A7 | 81.2 | 0 | 100 | 82.4 | 98.8 | 69 | 34.7 | 21.7 | 41.3 | 52.2 | 19.6 |
| (n=69) | (n=98) | (n=68) | (n=85) | (n=84) | (n=58) | (n=95) | (n=97) | (n=126) | (n=90) | (n=112) | |
| NB2-4t MNa | WT | Ubx1 | poxN>Ubx | ||||||||
| T1-T2 | 0 | 0 | 68.8 | ||||||||
| (n=29) | (n=20) | (n=32) | |||||||||
| T3 | 64.7 | 0 | 75 | ||||||||
| (n=17) | (n=11) | (n=16) | |||||||||
| A1-A7 | 0 | 0 | ND | ||||||||
| (n=70) | (n=12)* |
| GW . | WT . | Ubx1 . | en>Ubx . | hs-Ubx (3.5 hours AEL) . | hs-Ubx (12 hours AEL) . | AntpW10 . | en>Antp . | Ubx1/+ . | AntpW10,Ubx1/+ . | AntpW10,Ubx1/AntpW10 . | AntpW10,Ubx1 . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| T1-T2 | 0 | 0 | 80 | 0 | 21.9 | 35 | 0 | 0 | 2.8 | ND | ND |
| (n=55) | (n=28) | (n=20) | (n=27) | (n=64) | (n=20) | (n=28) | (n=28) | (n=36) | |||
| T3 | 55.6 | 0 | 90 | 100 | 90.6 | 90 | 30.8 | 7.1 | 16.7 | 36.4 | 23.5 |
| (n=27) | (n=14) | (n=10) | (n=12) | (n=32) | (n=10) | (n=13) | (n=14) | (n=18) | (n=22) | (n=17) | |
| A1-A7 | 81.2 | 0 | 100 | 82.4 | 98.8 | 69 | 34.7 | 21.7 | 41.3 | 52.2 | 19.6 |
| (n=69) | (n=98) | (n=68) | (n=85) | (n=84) | (n=58) | (n=95) | (n=97) | (n=126) | (n=90) | (n=112) | |
| NB2-4t MNa | WT | Ubx1 | poxN>Ubx | ||||||||
| T1-T2 | 0 | 0 | 68.8 | ||||||||
| (n=29) | (n=20) | (n=32) | |||||||||
| T3 | 64.7 | 0 | 75 | ||||||||
| (n=17) | (n=11) | (n=16) | |||||||||
| A1-A7 | 0 | 0 | ND | ||||||||
| (n=70) | (n=12)* |
Shown are percentages of motoneurons that were either positive for activated Caspase 3 or that had already been removed from the CNS.
n, the number of hemisegments counted.
ND, not determined.
A1 only.