Table 1.

Impact of Cx43 ablation on female fertility

GenotypeNumberNumber of pupsNumber of littersAverage pups/litterOvulation(ova/ovary)*Serum P4(ng/ml)*
Cx43fl/fl 37 419 65 6.4 19±2 84±12 
Cx43d/d 7 35 13 2.6 15±1 95±3 
GenotypeNumberNumber of pupsNumber of littersAverage pups/litterOvulation(ova/ovary)*Serum P4(ng/ml)*
Cx43fl/fl 37 419 65 6.4 19±2 84±12 
Cx43d/d 7 35 13 2.6 15±1 95±3 

Serum P concentrations were measured by radioimmunoassay (RIA) at the core facility of University of Virginia at Charlottesville. The values are expressed as mean±s.e.m.

*

n=5.

Thirteen female mice were placed in the breeding program; six mice did not give birth.

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