Analysis of adrenal weight and basal level ACTH measurement of 30-week-old Sf1/Crelow-β-catenin knockout mice
| . | Adrenal mass (normalized) . | Basal ACTH (pg/ml) . |
|---|---|---|
| Wild type | 1.31×10−4±1.83×10−5 | 64.29±31.16 |
| KO: cortical decline | 9.88×10−5±5.73×10−6* | 168.77±80.90* |
| KO: non-cortical decline | 1.35×10−4±1.99×10−5 | 59.58±38.07 |
| . | Adrenal mass (normalized) . | Basal ACTH (pg/ml) . |
|---|---|---|
| Wild type | 1.31×10−4±1.83×10−5 | 64.29±31.16 |
| KO: cortical decline | 9.88×10−5±5.73×10−6* | 168.77±80.90* |
| KO: non-cortical decline | 1.35×10−4±1.99×10−5 | 59.58±38.07 |
The mice were separated into wild type, KO-histological failure and KO-non-histological failure groups. The mass of adrenal glands and the whole mouse were obtained at time of euthanasia. The adrenal mass was normalized to the total body weight (*P<0.05 versus wild type and KO non-histological failure). The basal levels of ACTH were measured as described in the Materials and methods (*P<0.05 versus wild type and KO non-histological failure).