Potential mRNA targets of HOW
| Fold of change* . | Gene . | Conserved . | DM only . | DP only . |
|---|---|---|---|---|
| 8.3 | CG1221 (miple) | 0 | 1 | 2 |
| 5.7 | CG11357 | 0 | 2 | 0 |
| 4.6 | CG5973 | 0 | 1 | 3 |
| 3.0 | CG4193 | 0 | 1 | 1 |
| 3.0 | CG18543 | 0 | 1 | 1 |
| 2.7 | CG11143 | 0 | 1 | 1 |
| 2.6 | CG6207 | 0 | 1 | 3 |
| 2.4 | CG30035 | 0 | 1 | 1 |
| 2.3 | CG13795 | 0 | 1 | 1 |
| 2.2 | CG3158 | 1 | 0 | 0 |
| 2.1 | CG5621 | 1 | 0 | 0 |
| 2.0 | CG14889 | 2 | 1 | 7 |
| 1.9 | CG9670 (falten) | 2 | 1 | 0 |
| 1.9 | CG11064 | 0 | 1 | 3 |
| 1.8 | CG10460 | 0 | 1 | 2 |
| 1.8 | CG2065 | 0 | 1 | 0 |
| 1.8 | CG13920 | 1 | 0 | 0 |
| 1.8 | CG7272 | 1 | 1 | 1 |
| 1.8 | CG31638 | 1 | 1 | 2 |
| 1.8 | CG6448 | 0 | 1 | 0 |
| 1.7 | CG5992 | 0 | 2 | 1 |
| 1.7 | CG1633 | 0 | 1 | 1 |
| 1.7 | CG18661 | 0 | 1 | 0 |
| 1.7 | CG1667 | 0 | 1 | 5 |
| 1.6 | CG17734 | 0 | 1 | 2 |
| 1.6 | CG9629 | 0 | 1 | 1 |
| 1.6 | CG2520 (lap) | 1 | 4 | 3 |
| 1.6 | CG10120 | 0 | 1 | 1 |
| 1.6 | CG11267 | 0 | 1 | 0 |
| 1.6 | CG7904 (punt) | 2 | 0 | 0 |
| 1.6 | CG32920 | 0 | 2 | 2 |
| 1.5 | CG18319 | 0 | 3 | 0 |
| 1.5 | CG2803 | 0 | 1 | 1 |
| 1.5 | CG7334 | 0 | 1 | 2 |
| 1.5 | CG10691 | 1 | 1 | 0 |
| 1.5 | CG8327 | 0 | 2 | 0 |
| 1.5 | CG13928 | 0 | 2 | 3 |
| Fold of change* . | Gene . | Conserved . | DM only . | DP only . |
|---|---|---|---|---|
| 8.3 | CG1221 (miple) | 0 | 1 | 2 |
| 5.7 | CG11357 | 0 | 2 | 0 |
| 4.6 | CG5973 | 0 | 1 | 3 |
| 3.0 | CG4193 | 0 | 1 | 1 |
| 3.0 | CG18543 | 0 | 1 | 1 |
| 2.7 | CG11143 | 0 | 1 | 1 |
| 2.6 | CG6207 | 0 | 1 | 3 |
| 2.4 | CG30035 | 0 | 1 | 1 |
| 2.3 | CG13795 | 0 | 1 | 1 |
| 2.2 | CG3158 | 1 | 0 | 0 |
| 2.1 | CG5621 | 1 | 0 | 0 |
| 2.0 | CG14889 | 2 | 1 | 7 |
| 1.9 | CG9670 (falten) | 2 | 1 | 0 |
| 1.9 | CG11064 | 0 | 1 | 3 |
| 1.8 | CG10460 | 0 | 1 | 2 |
| 1.8 | CG2065 | 0 | 1 | 0 |
| 1.8 | CG13920 | 1 | 0 | 0 |
| 1.8 | CG7272 | 1 | 1 | 1 |
| 1.8 | CG31638 | 1 | 1 | 2 |
| 1.8 | CG6448 | 0 | 1 | 0 |
| 1.7 | CG5992 | 0 | 2 | 1 |
| 1.7 | CG1633 | 0 | 1 | 1 |
| 1.7 | CG18661 | 0 | 1 | 0 |
| 1.7 | CG1667 | 0 | 1 | 5 |
| 1.6 | CG17734 | 0 | 1 | 2 |
| 1.6 | CG9629 | 0 | 1 | 1 |
| 1.6 | CG2520 (lap) | 1 | 4 | 3 |
| 1.6 | CG10120 | 0 | 1 | 1 |
| 1.6 | CG11267 | 0 | 1 | 0 |
| 1.6 | CG7904 (punt) | 2 | 0 | 0 |
| 1.6 | CG32920 | 0 | 2 | 2 |
| 1.5 | CG18319 | 0 | 3 | 0 |
| 1.5 | CG2803 | 0 | 1 | 1 |
| 1.5 | CG7334 | 0 | 1 | 2 |
| 1.5 | CG10691 | 1 | 1 | 0 |
| 1.5 | CG8327 | 0 | 2 | 0 |
| 1.5 | CG13928 | 0 | 2 | 3 |
The five genes that were analyzed further because their sequences indicated possible roles in the process of mesoderm spreading are shown in bold. *Indicates the fold of change of expression in howgermline clone mutant embryos compared with wild type. Conserved, HOW response element location is conserved between D. melanogaster and D. pseudoobscura; DM only, HOW response element appears only in D. melanogaster; DP only, HOW response element appears only in D. pseudoobscura.