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Table 2.

Malignant transformation of epidermal tumours in DMBA-treated mice

Taf4eplox/loxTaf4ep-/-
Number of mice 11 
Number of tumours 24 
Taf4eplox/loxTaf4ep-/-
Number of mice 11 
Number of tumours 24 
MiceTumoursMiceTumours
Squamous cell hyperplasia 
Squamous cell papilloma 10 
Squamous cell carcinoma 12 
Melanocytic tumour 12 
MiceTumoursMiceTumours
Squamous cell hyperplasia 
Squamous cell papilloma 10 
Squamous cell carcinoma 12 
Melanocytic tumour 12 

DMBA-treated oil- or Tam-injected animals were sacrificed after 35 weeks and biopsies of tumours subjected to histological examination. The total number of sacrificed mice and of epidermal tumours analysed in each group are indicated at the top of the table. Below, the frequency of the different types of tumours is indicated for each group.

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