. | Taf4eplox/lox . | Taf4ep-/- . |
---|---|---|
Number of mice | 8 | 11 |
Number of tumours | 9 | 24 |
. | Taf4eplox/lox . | Taf4ep-/- . |
---|---|---|
Number of mice | 8 | 11 |
Number of tumours | 9 | 24 |
. | Mice . | Tumours . | Mice . | Tumours . |
---|---|---|---|---|
Squamous cell hyperplasia | 5 | 5 | 1 | 1 |
Squamous cell papilloma | 3 | 3 | 5 | 10 |
Squamous cell carcinoma | 1 | 1 | 7 | 12 |
Melanocytic tumour | 0 | 0 | 4 | 12 |
. | Mice . | Tumours . | Mice . | Tumours . |
---|---|---|---|---|
Squamous cell hyperplasia | 5 | 5 | 1 | 1 |
Squamous cell papilloma | 3 | 3 | 5 | 10 |
Squamous cell carcinoma | 1 | 1 | 7 | 12 |
Melanocytic tumour | 0 | 0 | 4 | 12 |
DMBA-treated oil- or Tam-injected animals were sacrificed after 35 weeks and biopsies of tumours subjected to histological examination. The total number of sacrificed mice and of epidermal tumours analysed in each group are indicated at the top of the table. Below, the frequency of the different types of tumours is indicated for each group.