. | Total neural cells . | Mitotic index (%) . | Ectopic pH3+ nuclei (%) . | Average L/W ratio . |
---|---|---|---|---|
Wild type | 25,315 | 5.35 (390/7295) | 5.45 (27/495) | 2.33±0.45 (n=100) |
lulu | 23,205 | 5.32 (373/7013) | 19.92 (47/236) | 1.44±0.29 (n=78) |
. | Total neural cells . | Mitotic index (%) . | Ectopic pH3+ nuclei (%) . | Average L/W ratio . |
---|---|---|---|---|
Wild type | 25,315 | 5.35 (390/7295) | 5.45 (27/495) | 2.33±0.45 (n=100) |
lulu | 23,205 | 5.32 (373/7013) | 19.92 (47/236) | 1.44±0.29 (n=78) |
Total anterior neural cells at E8.5 were counted and averaged for two wild-type and three lulu mutant embryos. The mitotic index[phospho-histone-H3-positive (pH3+) nuclei/total nuclei] was unchanged in lulu mutants. However, there was a 3.6-fold increase in ectopic mitotic nuclei in lulu embryos. Nuclear length:width (L/W)ratio was defined as the longest axis of the nucleus (L) divided by the orthogonal axis (W). ±, 1 standard deviation.