The Company of Biologists

Table 1.

Frequencies of genotypes in progeny from heterozygote intercrosses

				ΔE3/ΔE3 embryos
	Genotype						Growth arrest
Stage	+/+	+/ΔE3	ΔE3/ΔE3	Grossly normal	Mild	Severe^{^*}	Deteriorated	Resorbed^{^†}
E9.5	80 (26.5%)	153 (50.7%)	69 (22.8%)	5	35	29	0	0
E10.5	47 (22.2%)	114 (53.8%)	51 (24.1%)	4	18	16	13	0
E11.5	26 (32.1%)	41 (50.6%)	14 (17.3%)	1	1	1	11	0
E12.5	4 (26.7%)	5 (33.3%)	6 (40.0%)	0	0	0	5	1
E14.5	2 (40.0%)	2 (40.0%)	1 (20.0%)	0	0	0	0	1
E18.5	6 (42.9%)	8 (57.1%)	0 (0.0%)
Live born	72 (37.7%)	119 (62.3%)	0 (0.0%)

				ΔE3/ΔE3 embryos
	Genotype						Growth arrest
Stage	+/+	+/ΔE3	ΔE3/ΔE3	Grossly normal	Mild	Severe^{^*}	Deteriorated	Resorbed^{^†}
E9.5	80 (26.5%)	153 (50.7%)	69 (22.8%)	5	35	29	0	0
E10.5	47 (22.2%)	114 (53.8%)	51 (24.1%)	4	18	16	13	0
E11.5	26 (32.1%)	41 (50.6%)	14 (17.3%)	1	1	1	11	0
E12.5	4 (26.7%)	5 (33.3%)	6 (40.0%)	0	0	0	5	1
E14.5	2 (40.0%)	2 (40.0%)	1 (20.0%)	0	0	0	0	1
E18.5	6 (42.9%)	8 (57.1%)	0 (0.0%)
Live born	72 (37.7%)	119 (62.3%)	0 (0.0%)

Embryos with severe growth arrest, but they still had heartbeats

Only yolk sacs were obtained