Summary of gene expression in the developing kidney
| Gene . | Stage . | Cp2/1+/tra . | Cp2/1tra/tra . | P . |
|---|---|---|---|---|
| Atp6b1 | E13 | ND | ND | |
| E15 | 9.41±3.84 | 0.28±0.16 | <0.005 | |
| E18 | 104.48±12.76 | 10.80±4.26 | <0.001 | |
| P0 | 100±26.02 | 8.62±0.88 | <0.005 | |
| pendrin | E13 | ND | ND | |
| E15 | 2.93±2.12 | 0.14±0.00 | <0.001 | |
| E18 | 44.40±14.40 | 0.32±0.00 | <0.001 | |
| P0 | 100±25.54 | 2.98±1.79 | <0.001 | |
| keratin 7 | E13 | 7.10±0.06 | 5.00±1.55 | 0.06 |
| E15 | 25.35±0.00 | 12.37±2.60 | <0.01 | |
| E18 | 83.00±0.00 | 51.6±6.69 | <0.001 | |
| P0 | 100±0.01 | 58.72±7.36 | 0.01 | |
| Scnn1b | E13 | ND | ND | |
| E15 | 25.32±6.43 | 18.40±3.21 | 0.12 | |
| E18 | 82.23±5.56 | 59.39±12.9 | <0.05 | |
| P0 | 100±11.72 | 65.62±5.76 | 0.01 | |
| Aqp2 | E13 | ND | ND | |
| E15 | 2.97±1.73 | 1.34±0.64 | 0.17 | |
| E18 | 69.01±22.82 | 51.77±11.11 | 0.23 | |
| P0 | 100±33.50 | 77.65±9.49 | 0.32 | |
| keratin 19 | E13 | 6.79±0.97 | 6.90±2.37 | 0.93 |
| E15 | 52.84±6.95 | 57.15±11.44 | 0.54 | |
| E18 | 88.01±10.19 | 160.37±14.83 | <0.001 | |
| P0 | 100±25.52 | 176.40±73.74 | <0.005 | |
| Gk-6 | E13 | ND | ND | |
| E15 | 3.42±0.82 | 1.45±0.44 | 0.005 | |
| E18 | 105.58±18.15 | 13.16±5.69 | <0.001 | |
| P0 | 100±15.72 | 14.16±2.52 | <0.001 | |
| Clcnkb | E13 | ND | ND | |
| E15 | 4.52±2.10 | ND | ||
| E18 | 66.58±14.74 | 17.18±5.39 | <0.001 | |
| P0 | 100±16.37 | 21.09±3.60 | <0.001 |
| Gene . | Stage . | Cp2/1+/tra . | Cp2/1tra/tra . | P . |
|---|---|---|---|---|
| Atp6b1 | E13 | ND | ND | |
| E15 | 9.41±3.84 | 0.28±0.16 | <0.005 | |
| E18 | 104.48±12.76 | 10.80±4.26 | <0.001 | |
| P0 | 100±26.02 | 8.62±0.88 | <0.005 | |
| pendrin | E13 | ND | ND | |
| E15 | 2.93±2.12 | 0.14±0.00 | <0.001 | |
| E18 | 44.40±14.40 | 0.32±0.00 | <0.001 | |
| P0 | 100±25.54 | 2.98±1.79 | <0.001 | |
| keratin 7 | E13 | 7.10±0.06 | 5.00±1.55 | 0.06 |
| E15 | 25.35±0.00 | 12.37±2.60 | <0.01 | |
| E18 | 83.00±0.00 | 51.6±6.69 | <0.001 | |
| P0 | 100±0.01 | 58.72±7.36 | 0.01 | |
| Scnn1b | E13 | ND | ND | |
| E15 | 25.32±6.43 | 18.40±3.21 | 0.12 | |
| E18 | 82.23±5.56 | 59.39±12.9 | <0.05 | |
| P0 | 100±11.72 | 65.62±5.76 | 0.01 | |
| Aqp2 | E13 | ND | ND | |
| E15 | 2.97±1.73 | 1.34±0.64 | 0.17 | |
| E18 | 69.01±22.82 | 51.77±11.11 | 0.23 | |
| P0 | 100±33.50 | 77.65±9.49 | 0.32 | |
| keratin 19 | E13 | 6.79±0.97 | 6.90±2.37 | 0.93 |
| E15 | 52.84±6.95 | 57.15±11.44 | 0.54 | |
| E18 | 88.01±10.19 | 160.37±14.83 | <0.001 | |
| P0 | 100±25.52 | 176.40±73.74 | <0.005 | |
| Gk-6 | E13 | ND | ND | |
| E15 | 3.42±0.82 | 1.45±0.44 | 0.005 | |
| E18 | 105.58±18.15 | 13.16±5.69 | <0.001 | |
| P0 | 100±15.72 | 14.16±2.52 | <0.001 | |
| Clcnkb | E13 | ND | ND | |
| E15 | 4.52±2.10 | ND | ||
| E18 | 66.58±14.74 | 17.18±5.39 | <0.001 | |
| P0 | 100±16.37 | 21.09±3.60 | <0.001 |
Relative expression levels (mean±s.d., n=4-9) were normalized to cyclophilin D.
ND, not detected.