A Functional classes | ||||||||||||
Gene class* | Total on array | Dauer-enriched† | Transient | Early | Climbing | Late | ||||||
Genome | 17761 | 540 | 195 | 538 | 386 | 325 | ||||||
Glycolysis | 21 | 6.5 (3) | ||||||||||
TCA | 30 | 9.1 (6) | ||||||||||
Muscle expressed genes | 1329 | 2.6 (76) | ||||||||||
Hedgehog-like | 46 | 12 (10) | ||||||||||
Patched-like/NPC | 22 | 17 (7) | ||||||||||
Cytochrome P450 enzymes | 81 | 3.2 (8) | 5.6 (5) | |||||||||
UDP-Glucoronosyltransferase | 73 | 4.9 (11) | 4.9 (4) | |||||||||
Nuclear hormone receptors | 270 | 3.3 (10) | ||||||||||
Peroxisome localization | 18 | 15.0 (3) | ||||||||||
Collagen | 179 | 2.8 (11) | 12 (41) | |||||||||
Worm-yeast orthologs | 1921 | 1.7 (72) | ||||||||||
Lectins | 220 | 2.8 (19) | ||||||||||
Lipid metabolism genes | 303 | 2.9 (27) | ||||||||||
Cell adhesion genes | 49 | 13.3 (12) | ||||||||||
Cell structure genes | 219 | 3.0 (12) | ||||||||||
Mitochondria localization | 179 | 4.6 (18) | ||||||||||
Biosynthesis | 478 | 2.1 (31) | 5.1 (53) | |||||||||
Basement membrane | 14 | 13.0 (4) | ||||||||||
Fatty acid oxidation | 48 | 4.8 (5) | ||||||||||
Other phosphatases | 31 | 5.3 (5) | ||||||||||
Carbohydrate metabolism | 121 | 4.9 (13) | ||||||||||
Amino acid metabolism | 104 | 5.0 (16) | 7.0 (16) | |||||||||
Energy generation genes | 117 | 6.2 (16) | ||||||||||
Translation factors | 41 | 4.8 (6) | ||||||||||
Transporters | 407 | 2.9 (13) | 2.9 (36) | |||||||||
Small molecule transport | 561 | 2.2 (37) | ||||||||||
Passive channels | 203 | 3.2 (20) | ||||||||||
Protein degradation | 250 | 2.2 (17) | ||||||||||
Protease | 186 | 3.3 (19) | ||||||||||
B Gene expression mountains | ||||||||||||
Gene class* | Total on array | Dauer-enriched† | Transient | Early | Climbing | Late | ||||||
Genome | 17761 | 540 | 195 | 538 | 386 | 325 | ||||||
Mount 01 | 1818 | 1.7 (34) | 1.5 (85) | |||||||||
Mount 06 | 909 | 4.5 (126) | 2.8 (28) | |||||||||
Mount 08 | 803 | 2.2 (55) | 2.6 (45) | |||||||||
Mount 14 | 353 | 6.3 (49) | 26 (169) | |||||||||
Mount 15 | 247 | 8.6 (65) | ||||||||||
Mount 16 | 230 | 5.6 (28) | 11.5 (49) | |||||||||
Mount 19 | 189 | 8.8 (51) | 5.8 (24) | |||||||||
Mount 20 | 160 | 3.9 (19) | 5.1 (18) | |||||||||
Mount 21 | 154 | 2.8 (13) | 16.0 (27) | 4.0 (19) | ||||||||
Mount 22 | 151 | 2.8 (13) | ||||||||||
Mount 23 | 143 | 3.8 (12) | ||||||||||
Mount 24 | 133 | 10.0 (15) | 7.9 (32) | |||||||||
Mount 27 | 87 | 11.0 (30) | ||||||||||
Mount 29 | 40 | 12 (9) | ||||||||||
Mount 31 | 25 | 9.2 (7) | ||||||||||
Mount 41 | 7 | 19.0 (4) |
A Functional classes | ||||||||||||
Gene class* | Total on array | Dauer-enriched† | Transient | Early | Climbing | Late | ||||||
Genome | 17761 | 540 | 195 | 538 | 386 | 325 | ||||||
Glycolysis | 21 | 6.5 (3) | ||||||||||
TCA | 30 | 9.1 (6) | ||||||||||
Muscle expressed genes | 1329 | 2.6 (76) | ||||||||||
Hedgehog-like | 46 | 12 (10) | ||||||||||
Patched-like/NPC | 22 | 17 (7) | ||||||||||
Cytochrome P450 enzymes | 81 | 3.2 (8) | 5.6 (5) | |||||||||
UDP-Glucoronosyltransferase | 73 | 4.9 (11) | 4.9 (4) | |||||||||
Nuclear hormone receptors | 270 | 3.3 (10) | ||||||||||
Peroxisome localization | 18 | 15.0 (3) | ||||||||||
Collagen | 179 | 2.8 (11) | 12 (41) | |||||||||
Worm-yeast orthologs | 1921 | 1.7 (72) | ||||||||||
Lectins | 220 | 2.8 (19) | ||||||||||
Lipid metabolism genes | 303 | 2.9 (27) | ||||||||||
Cell adhesion genes | 49 | 13.3 (12) | ||||||||||
Cell structure genes | 219 | 3.0 (12) | ||||||||||
Mitochondria localization | 179 | 4.6 (18) | ||||||||||
Biosynthesis | 478 | 2.1 (31) | 5.1 (53) | |||||||||
Basement membrane | 14 | 13.0 (4) | ||||||||||
Fatty acid oxidation | 48 | 4.8 (5) | ||||||||||
Other phosphatases | 31 | 5.3 (5) | ||||||||||
Carbohydrate metabolism | 121 | 4.9 (13) | ||||||||||
Amino acid metabolism | 104 | 5.0 (16) | 7.0 (16) | |||||||||
Energy generation genes | 117 | 6.2 (16) | ||||||||||
Translation factors | 41 | 4.8 (6) | ||||||||||
Transporters | 407 | 2.9 (13) | 2.9 (36) | |||||||||
Small molecule transport | 561 | 2.2 (37) | ||||||||||
Passive channels | 203 | 3.2 (20) | ||||||||||
Protein degradation | 250 | 2.2 (17) | ||||||||||
Protease | 186 | 3.3 (19) | ||||||||||
B Gene expression mountains | ||||||||||||
Gene class* | Total on array | Dauer-enriched† | Transient | Early | Climbing | Late | ||||||
Genome | 17761 | 540 | 195 | 538 | 386 | 325 | ||||||
Mount 01 | 1818 | 1.7 (34) | 1.5 (85) | |||||||||
Mount 06 | 909 | 4.5 (126) | 2.8 (28) | |||||||||
Mount 08 | 803 | 2.2 (55) | 2.6 (45) | |||||||||
Mount 14 | 353 | 6.3 (49) | 26 (169) | |||||||||
Mount 15 | 247 | 8.6 (65) | ||||||||||
Mount 16 | 230 | 5.6 (28) | 11.5 (49) | |||||||||
Mount 19 | 189 | 8.8 (51) | 5.8 (24) | |||||||||
Mount 20 | 160 | 3.9 (19) | 5.1 (18) | |||||||||
Mount 21 | 154 | 2.8 (13) | 16.0 (27) | 4.0 (19) | ||||||||
Mount 22 | 151 | 2.8 (13) | ||||||||||
Mount 23 | 143 | 3.8 (12) | ||||||||||
Mount 24 | 133 | 10.0 (15) | 7.9 (32) | |||||||||
Mount 27 | 87 | 11.0 (30) | ||||||||||
Mount 29 | 40 | 12 (9) | ||||||||||
Mount 31 | 25 | 9.2 (7) | ||||||||||
Mount 41 | 7 | 19.0 (4) |
Over-represented functional classes in the dauer recovery subgroups. For clarity, gene groups with P>0.001 are not listed. Gene lists are shown in supplemental Table S7.
The representation factor is shown and the number of overlapping genes between the two groups is in parentheses. All representation factors are significant at P<0.001. The probability was determined using the normal approximation of the hypergeometric probability distribution.