Table 2.

Dauer recovery

A Functional classes
 

 

 

 

 

 

 
Gene class* Total on array Dauer-enriched Transient Early Climbing Late 
Genome 17761 540 195 538 386 325 
Glycolysis 21    6.5 (3)  
TCA 30    9.1 (6)  
Muscle expressed genes 1329    2.6 (76)  
Hedgehog-like 46     12 (10) 
Patched-like/NPC 22     17 (7) 
Cytochrome P450 enzymes 81 3.2 (8) 5.6 (5)    
UDP-Glucoronosyltransferase 73 4.9 (11) 4.9 (4)    
Nuclear hormone receptors 270  3.3 (10)    
Peroxisome localization 18  15.0 (3)    
Collagen 179    2.8 (11) 12 (41) 
Worm-yeast orthologs 1921    1.7 (72)  
Lectins 220   2.8 (19)   
Lipid metabolism genes 303 2.9 (27)     
Cell adhesion genes 49     13.3 (12) 
Cell structure genes 219     3.0 (12) 
Mitochondria localization 179    4.6 (18)  
Biosynthesis 478   2.1 (31) 5.1 (53)  
Basement membrane 14    13.0 (4)  
Fatty acid oxidation 48    4.8 (5)  
Other phosphatases 31   5.3 (5)   
Carbohydrate metabolism 121    4.9 (13)  
Amino acid metabolism 104   5.0 (16) 7.0 (16)  
Energy generation genes 117    6.2 (16)  
Translation factors 41   4.8 (6)   
Transporters 407  2.9 (13) 2.9 (36)   
Small molecule transport 561 2.2 (37)     
Passive channels 203 3.2 (20)     
Protein degradation 250   2.2 (17)   
Protease 186   3.3 (19)   
B Gene expression mountains
 
      
Gene class* Total on array Dauer-enriched Transient Early Climbing Late 
Genome 17761 540 195 538 386 325 
Mount 01 1818  1.7 (34) 1.5 (85)   
Mount 06 909 4.5 (126) 2.8 (28)    
Mount 08 803 2.2 (55)   2.6 (45)  
Mount 14 353    6.3 (49) 26 (169) 
Mount 15 247 8.6 (65)     
Mount 16 230    5.6 (28) 11.5 (49) 
Mount 19 189   8.8 (51) 5.8 (24)  
Mount 20 160   3.9 (19) 5.1 (18)  
Mount 21 154 2.8 (13) 16.0 (27) 4.0 (19)   
Mount 22 151 2.8 (13)     
Mount 23 143    3.8 (12)  
Mount 24 133  10.0 (15) 7.9 (32)   
Mount 27 87   11.0 (30)   
Mount 29 40     12 (9) 
Mount 31 25   9.2 (7)   
Mount 41   19.0 (4)   
A Functional classes
 

 

 

 

 

 

 
Gene class* Total on array Dauer-enriched Transient Early Climbing Late 
Genome 17761 540 195 538 386 325 
Glycolysis 21    6.5 (3)  
TCA 30    9.1 (6)  
Muscle expressed genes 1329    2.6 (76)  
Hedgehog-like 46     12 (10) 
Patched-like/NPC 22     17 (7) 
Cytochrome P450 enzymes 81 3.2 (8) 5.6 (5)    
UDP-Glucoronosyltransferase 73 4.9 (11) 4.9 (4)    
Nuclear hormone receptors 270  3.3 (10)    
Peroxisome localization 18  15.0 (3)    
Collagen 179    2.8 (11) 12 (41) 
Worm-yeast orthologs 1921    1.7 (72)  
Lectins 220   2.8 (19)   
Lipid metabolism genes 303 2.9 (27)     
Cell adhesion genes 49     13.3 (12) 
Cell structure genes 219     3.0 (12) 
Mitochondria localization 179    4.6 (18)  
Biosynthesis 478   2.1 (31) 5.1 (53)  
Basement membrane 14    13.0 (4)  
Fatty acid oxidation 48    4.8 (5)  
Other phosphatases 31   5.3 (5)   
Carbohydrate metabolism 121    4.9 (13)  
Amino acid metabolism 104   5.0 (16) 7.0 (16)  
Energy generation genes 117    6.2 (16)  
Translation factors 41   4.8 (6)   
Transporters 407  2.9 (13) 2.9 (36)   
Small molecule transport 561 2.2 (37)     
Passive channels 203 3.2 (20)     
Protein degradation 250   2.2 (17)   
Protease 186   3.3 (19)   
B Gene expression mountains
 
      
Gene class* Total on array Dauer-enriched Transient Early Climbing Late 
Genome 17761 540 195 538 386 325 
Mount 01 1818  1.7 (34) 1.5 (85)   
Mount 06 909 4.5 (126) 2.8 (28)    
Mount 08 803 2.2 (55)   2.6 (45)  
Mount 14 353    6.3 (49) 26 (169) 
Mount 15 247 8.6 (65)     
Mount 16 230    5.6 (28) 11.5 (49) 
Mount 19 189   8.8 (51) 5.8 (24)  
Mount 20 160   3.9 (19) 5.1 (18)  
Mount 21 154 2.8 (13) 16.0 (27) 4.0 (19)   
Mount 22 151 2.8 (13)     
Mount 23 143    3.8 (12)  
Mount 24 133  10.0 (15) 7.9 (32)   
Mount 27 87   11.0 (30)   
Mount 29 40     12 (9) 
Mount 31 25   9.2 (7)   
Mount 41   19.0 (4)   
*

Over-represented functional classes in the dauer recovery subgroups. For clarity, gene groups with P>0.001 are not listed. Gene lists are shown in supplemental Table S7.

The representation factor is shown and the number of overlapping genes between the two groups is in parentheses. All representation factors are significant at P<0.001. The probability was determined using the normal approximation of the hypergeometric probability distribution.

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