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Table 1.

Genetic interactions between nmy-1 and genes in the let-502/mel-11 elongation pathway

	20°C			25°C
Genotype	Hatching (%)	L1 arrest (% of hatched)^*	Hatching (%)	L1 arrest (% of hatched)^*
mel-11(it26)	4	-^{^†}	0	-
mel-11(it26); nmy-1(RNAi)	71	Range of arrest	-	-
mel-11(it26); nmy-1(sb92)/+	23	0	-	-
mel-11(it26); nmy-1(sb92)	68	0	-	-
mel-11(it26); nmy-1(sb113)/+	48	5	23	44
mel-11(it26); nmy-1(sb113)	75	62	64	84^{^‡}
mel-11(it26); nmy-1(sb115)/+	35	56	27	74
let-502(sb108)	100	0	92	0
let-502(sb108); nmy-1(sb115)	-	-	88	82
mel-11(it26); spc-1(ra409)/+	7	100	-	-
mel-11(sb55)	-	-	6	0
sma-1(e30)	-	-	95	7
mel-11(sb55); sma-1(e30)	-	-	94	86
mel-11(it26); sma-1(e30)	68	92	-	-

	20°C			25°C
Genotype	Hatching (%)	L1 arrest (% of hatched)^*	Hatching (%)	L1 arrest (% of hatched)^*
mel-11(it26)	4	-^{^†}	0	-
mel-11(it26); nmy-1(RNAi)	71	Range of arrest	-	-
mel-11(it26); nmy-1(sb92)/+	23	0	-	-
mel-11(it26); nmy-1(sb92)	68	0	-	-
mel-11(it26); nmy-1(sb113)/+	48	5	23	44
mel-11(it26); nmy-1(sb113)	75	62	64	84^{^‡}
mel-11(it26); nmy-1(sb115)/+	35	56	27	74
let-502(sb108)	100	0	92	0
let-502(sb108); nmy-1(sb115)	-	-	88	82
mel-11(it26); spc-1(ra409)/+	7	100	-	-
mel-11(sb55)	-	-	6	0
sma-1(e30)	-	-	95	7
mel-11(sb55); sma-1(e30)	-	-	94	86
mel-11(it26); sma-1(e30)	68	92	-	-

The L1 arrest phenotype was like mlc-4 shown in Fig. 2, and differed from the slow-growing L1-L3 Lumpy Dpy larva observed in nmy-1 homozygotes alone.

†

Not determined.

‡

All non-arrested animals were Lumpy Dpy.

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