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Table 1.

Genetic interactions between nmy-1 and genes in the let-502/mel-11 elongation pathway

20°C
25°C
GenotypeHatching (%)L1 arrest (% of hatched)*Hatching (%)L1 arrest (% of hatched)*
mel-11(it26) - 
mel-11(it26); nmy-1(RNAi) 71 Range of arrest 
mel-11(it26); nmy-1(sb92)/+ 23 
mel-11(it26); nmy-1(sb92) 68 
mel-11(it26); nmy-1(sb113)/+ 48 23 44 
mel-11(it26); nmy-1(sb113) 75 62 64 84 
mel-11(it26); nmy-1(sb115)/+ 35 56 27 74 
let-502(sb108) 100 92 
let-502(sb108); nmy-1(sb115) 88 82 
mel-11(it26); spc-1(ra409)/+ 100 
mel-11(sb55) 
sma-1(e30) 95 
mel-11(sb55); sma-1(e30) 94 86 
mel-11(it26); sma-1(e30) 68 92 
20°C
25°C
GenotypeHatching (%)L1 arrest (% of hatched)*Hatching (%)L1 arrest (% of hatched)*
mel-11(it26) - 
mel-11(it26); nmy-1(RNAi) 71 Range of arrest 
mel-11(it26); nmy-1(sb92)/+ 23 
mel-11(it26); nmy-1(sb92) 68 
mel-11(it26); nmy-1(sb113)/+ 48 23 44 
mel-11(it26); nmy-1(sb113) 75 62 64 84 
mel-11(it26); nmy-1(sb115)/+ 35 56 27 74 
let-502(sb108) 100 92 
let-502(sb108); nmy-1(sb115) 88 82 
mel-11(it26); spc-1(ra409)/+ 100 
mel-11(sb55) 
sma-1(e30) 95 
mel-11(sb55); sma-1(e30) 94 86 
mel-11(it26); sma-1(e30) 68 92 
*

The L1 arrest phenotype was like mlc-4 shown in Fig. 2, and differed from the slow-growing L1-L3 Lumpy Dpy larva observed in nmy-1 homozygotes alone.

Not determined.

All non-arrested animals were Lumpy Dpy.

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