. | . | . | LPM . | . | . | . | Node region . | . | . | . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene . | Genotype . | Somites . | Left . | Right . | Bilateral . | Absent . | Normal . | Changed* . | Absent . | Total number . | ||||||||||
Nodal | +/+ or +/- | 0-6 | 100% | - | - | - | 100% | - | - | 10 | ||||||||||
6-10 | 40% | - | - | 60% | - | - | 100% | 5 | ||||||||||||
-/- | 0-6 | 19.05% | 19.05% | 14.3% | 47.6% | 19.05% | 14.3% | 66.7% | 21 | |||||||||||
6-10 | 50% | - | - | 50% | - | - | 100% | 2 | ||||||||||||
Leftb | +/+ or +/- | 4-7 | 100% | - | - | - | 8 | |||||||||||||
-/- | 4-7 | 31.2% | 18.8% | 25% | 25% | 16 | ||||||||||||||
Pitx2 | +/+ or +/- | 6-10 | 100% | - | - | - | 12 | |||||||||||||
-/- | 6-10 | 20% | 4% | 60% | 16% | 25 | ||||||||||||||
Ebaf floorplate-specific expression | ||||||||||||||||||||
Ebaf | +/+ or +/- | 2-6 | 100% | - | - | - | 6 | |||||||||||||
-/- | 2-6 | - | - | - | 100% | 11 |
. | . | . | LPM . | . | . | . | Node region . | . | . | . | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene . | Genotype . | Somites . | Left . | Right . | Bilateral . | Absent . | Normal . | Changed* . | Absent . | Total number . | ||||||||||
Nodal | +/+ or +/- | 0-6 | 100% | - | - | - | 100% | - | - | 10 | ||||||||||
6-10 | 40% | - | - | 60% | - | - | 100% | 5 | ||||||||||||
-/- | 0-6 | 19.05% | 19.05% | 14.3% | 47.6% | 19.05% | 14.3% | 66.7% | 21 | |||||||||||
6-10 | 50% | - | - | 50% | - | - | 100% | 2 | ||||||||||||
Leftb | +/+ or +/- | 4-7 | 100% | - | - | - | 8 | |||||||||||||
-/- | 4-7 | 31.2% | 18.8% | 25% | 25% | 16 | ||||||||||||||
Pitx2 | +/+ or +/- | 6-10 | 100% | - | - | - | 12 | |||||||||||||
-/- | 6-10 | 20% | 4% | 60% | 16% | 25 | ||||||||||||||
Ebaf floorplate-specific expression | ||||||||||||||||||||
Ebaf | +/+ or +/- | 2-6 | 100% | - | - | - | 6 | |||||||||||||
-/- | 2-6 | - | - | - | 100% | 11 |
In two individuals, Nodal expression was stronger at the right of the node; in one individual, Nodal expression was bilateral symmetric around the node.