Reduction of BMP signaling interferes with endoderm-mediated induction of epibranchials
| . | Transplants (genotype of host embryo) . | . | . | . | . | . | . | . | . | . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ganglia . | cas (wt) . | cas (cas) . | tar* (wt) . | tar* (cas) . | cas/tar* +nog (wt) . | cas/tar* +nog (cas) . | cas/tar* +2bMO (wt) . | cas/tar* +2bMO (cas) . | cas/tar* +2b/5MO (wt) . | cas/tar* +2b/5MO (cas) . | |||||||||
| Normal | 38 | 5 | 24 | 3 | 23 | 0 | 12 | 0 | 10 | 0 | |||||||||
| Reduced | 0 | 8 | 0 | 11 | 17 | 2 | 0 | 9 | 16 | 0 | |||||||||
| Absent | 0 | 0 | 0 | 2 | 0 | 19 | 0 | 4 | 0 | 19 | |||||||||
| . | Transplants (genotype of host embryo) . | . | . | . | . | . | . | . | . | . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ganglia . | cas (wt) . | cas (cas) . | tar* (wt) . | tar* (cas) . | cas/tar* +nog (wt) . | cas/tar* +nog (cas) . | cas/tar* +2bMO (wt) . | cas/tar* +2bMO (cas) . | cas/tar* +2b/5MO (wt) . | cas/tar* +2b/5MO (cas) . | |||||||||
| Normal | 38 | 5 | 24 | 3 | 23 | 0 | 12 | 0 | 10 | 0 | |||||||||
| Reduced | 0 | 8 | 0 | 11 | 17 | 2 | 0 | 9 | 16 | 0 | |||||||||
| Absent | 0 | 0 | 0 | 2 | 0 | 19 | 0 | 4 | 0 | 19 | |||||||||
Host embryos were injected with either 500 pg nog mRNA, 300 pg bmp2b-MO (2bMO) alone or 2bMO together with 1 ng bmp5-MO(5MO).