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Table 1.
The designed C-terminal mutants of SMA-2, SMA-3 and SMA-4
Proteins
.
C terminus
.
Description
.
SMA-3
SMT
Wild type
DME
Pseudophosphorylated
AMA
Non-phosphorylatable
ΔMT
Partially functional
ΔSMT
Non-functional
SMA-2
SIS
Wild type
DID
Pseudophosphorylated
SMA-4
SS
Wild type
DD
Pseudophosphorylated
AA
Non-phosphorylatable
SSIS
Simulate R-Smad
Proteins
.
C terminus
.
Description
.
SMA-3
SMT
Wild type
DME
Pseudophosphorylated
AMA
Non-phosphorylatable
ΔMT
Partially functional
ΔSMT
Non-functional
SMA-2
SIS
Wild type
DID
Pseudophosphorylated
SMA-4
SS
Wild type
DD
Pseudophosphorylated
AA
Non-phosphorylatable
SSIS
Simulate R-Smad
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