. | Time (min) . | FiO2 . | V̇Tot (ml kg–1 min–1) . | fL (min–1) . | VT (ml kg–1) . | V̇O2 (mmol kg–1 min–1) . | V̇Tot/V̇O2(ml mmol–1) . |
---|---|---|---|---|---|---|---|
Hypoxia | 0 | 21% | 591±105 | 7.6±1.0 | 78.1±11.1 | 1.64±0.07 | 363±72 |
15 | 12% | 700±148 | 8.6±1.9 | 81.9±3.0 | 1.70±0.09 | 409±82 | |
30 | 9% | 914±179 | 12.2±4.2 | 86.3±16.1 | 1.65±0.10 | 564±119 | |
45 | 7% | 1504±411† | 16.5±6.0 | 104.2±17.9 | 1.46±0.08† | 1080±333*,† | |
Control | 0 | 21% | 473±137 | 5.5±1.8 | 89.5±8.6 | 1.50±0.30 | 301±44 |
15 | 21% | 637±193 | 6.9±3.1 | 103.8±14.9 | 1.62±0.33 | 388±73 | |
30 | 21% | 743±240 | 8.1±3.5 | 100.8±12.9 | 1.52±0.34 | 468±72 | |
45 | 21% | 857±312 | 10.9±4.9 | 84.8±8.7 | 1.54±0.32 | 524±102 |
. | Time (min) . | FiO2 . | V̇Tot (ml kg–1 min–1) . | fL (min–1) . | VT (ml kg–1) . | V̇O2 (mmol kg–1 min–1) . | V̇Tot/V̇O2(ml mmol–1) . |
---|---|---|---|---|---|---|---|
Hypoxia | 0 | 21% | 591±105 | 7.6±1.0 | 78.1±11.1 | 1.64±0.07 | 363±72 |
15 | 12% | 700±148 | 8.6±1.9 | 81.9±3.0 | 1.70±0.09 | 409±82 | |
30 | 9% | 914±179 | 12.2±4.2 | 86.3±16.1 | 1.65±0.10 | 564±119 | |
45 | 7% | 1504±411† | 16.5±6.0 | 104.2±17.9 | 1.46±0.08† | 1080±333*,† | |
Control | 0 | 21% | 473±137 | 5.5±1.8 | 89.5±8.6 | 1.50±0.30 | 301±44 |
15 | 21% | 637±193 | 6.9±3.1 | 103.8±14.9 | 1.62±0.33 | 388±73 | |
30 | 21% | 743±240 | 8.1±3.5 | 100.8±12.9 | 1.52±0.34 | 468±72 | |
45 | 21% | 857±312 | 10.9±4.9 | 84.8±8.7 | 1.54±0.32 | 524±102 |
FiO2, inspired O2fraction; V̇Tot, total ventilation; fL, breathing frequency; VT, tidal volume; V̇O2, oxygen consumption rate; V̇Tot/V̇O2,air convection requirement
Values are means (± s.e.m.) after 10–15 minutes at each FiO2 (N=3)
Significant difference between hypoxia and normoxia-control treatments(P<0.05)
significant difference from time 0 (within species)