Dynamic properties of microtubules in growth cones
| Fluorescent molecule . | Average orthograde growth rate (μm/min) . | Orthograde translocation rate (μm/min) . | Retrograde translocation rate (μm/min) . | Neuron type . | Species . | Reference . |
|---|---|---|---|---|---|---|
| Rho-tubulin | 7.14±0.33 | Bag cell | Aplysia | (Kabir et al., 2001) | ||
| Rho-tubulin | 6.9±0.3 | Bag cell | Aplysia | (Schaefer et al., 2002) | ||
| Rho-tubulin | 8.4±0.4 (central) | 4.5±0.4 | 4.7±0.2 | Bag cell | Aplysia | (Lee and Suter, 2008) |
| 7.8±0.4 (peripheral) | ||||||
| Tubulin-GFP | 9.80±0.47 | Spinal cord | Xenopus | (Ma et al., 2004) | ||
| Rho-tubulin | 10.5±1.9 | Spinal cord | Xenopus | (Tanaka and Kirschner, 1991) | ||
| EB1-GFP | 10.22±0.5 | Spinal cord | Xenopus | (Ma et al., 2004) | ||
| EB3-GFP | 12 | Hippocampal | Mouse | (Stepanova et al., 2003) | ||
| EB3-GFP | 8.7±0.5 | Hippocampal | Rat | (Grabham et al., 2007) | ||
| EB3-GFP | 5.7±0.3 | SCG | Rat | (Myers et al., 2006) | ||
| Rho-tubulin | 7.7±0.9 | Cerebral cortical | Hamster | (Dent et al., 1999) | ||
| CLASP-GFP | 9.7±2.1 | Spinal cord | Xenopus | (Lee et al., 2004) |
| Fluorescent molecule . | Average orthograde growth rate (μm/min) . | Orthograde translocation rate (μm/min) . | Retrograde translocation rate (μm/min) . | Neuron type . | Species . | Reference . |
|---|---|---|---|---|---|---|
| Rho-tubulin | 7.14±0.33 | Bag cell | Aplysia | (Kabir et al., 2001) | ||
| Rho-tubulin | 6.9±0.3 | Bag cell | Aplysia | (Schaefer et al., 2002) | ||
| Rho-tubulin | 8.4±0.4 (central) | 4.5±0.4 | 4.7±0.2 | Bag cell | Aplysia | (Lee and Suter, 2008) |
| 7.8±0.4 (peripheral) | ||||||
| Tubulin-GFP | 9.80±0.47 | Spinal cord | Xenopus | (Ma et al., 2004) | ||
| Rho-tubulin | 10.5±1.9 | Spinal cord | Xenopus | (Tanaka and Kirschner, 1991) | ||
| EB1-GFP | 10.22±0.5 | Spinal cord | Xenopus | (Ma et al., 2004) | ||
| EB3-GFP | 12 | Hippocampal | Mouse | (Stepanova et al., 2003) | ||
| EB3-GFP | 8.7±0.5 | Hippocampal | Rat | (Grabham et al., 2007) | ||
| EB3-GFP | 5.7±0.3 | SCG | Rat | (Myers et al., 2006) | ||
| Rho-tubulin | 7.7±0.9 | Cerebral cortical | Hamster | (Dent et al., 1999) | ||
| CLASP-GFP | 9.7±2.1 | Spinal cord | Xenopus | (Lee et al., 2004) |
Rho, rhodamine; SCG, superior cervical ganglion