Interference among MLH1 foci in wild-type and Sycp3–/– oocytes
| . | . | . | Average interfocus distance (s.d.) . | . | . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Genotype . | Chromosome* . | Number of intervals . | μm . | % SC . | v̂ (s.e.)† . | P‡ . | Corr. ν§ . | |
| Wild type | 1 | 95 | 7.2 (2.8) | 51.4 (16.3) | 8.9 (1.3) | 0.3 | 7.5 | |
| 2 | 88 | 7.1 (2.3) | 52.7 (14.9) | 11.7 (1.7) | 0.3 | 10.1 | ||
| Sycp3–/– | 1 (total) | 31 | 12.4 (3.2) | 42.6 (12.7) | 11.5 (2.9) | 0.2 | 10.0 | |
| 1 syn. | 15 | 11.5 (3.2) | 41.9 (14.8) | 9.5 (3.4) | 0.5 | |||
| 1 unsyn. | 16 | 13.3 (3.1) | 43.2 (10.8) | 14.5 (5.1) | 0.4 | |||
| 2 (total) | 36 | 13.9 (5.0) | 48.2 (17.0) | 8.5 (2.0) | 0.05 | 7.3 | ||
| 2 syn. | 18 | 12.1 (3.4) | 41.8 (12.9) | 12.1 (4.0) | 0.2 | |||
| 2 unsyn. | 18 | 15.6 (5.7) | 54.5 (18.6) | 8.4 (2.7) | 0.03 | |||
| . | . | . | Average interfocus distance (s.d.) . | . | . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Genotype . | Chromosome* . | Number of intervals . | μm . | % SC . | v̂ (s.e.)† . | P‡ . | Corr. ν§ . | |
| Wild type | 1 | 95 | 7.2 (2.8) | 51.4 (16.3) | 8.9 (1.3) | 0.3 | 7.5 | |
| 2 | 88 | 7.1 (2.3) | 52.7 (14.9) | 11.7 (1.7) | 0.3 | 10.1 | ||
| Sycp3–/– | 1 (total) | 31 | 12.4 (3.2) | 42.6 (12.7) | 11.5 (2.9) | 0.2 | 10.0 | |
| 1 syn. | 15 | 11.5 (3.2) | 41.9 (14.8) | 9.5 (3.4) | 0.5 | |||
| 1 unsyn. | 16 | 13.3 (3.1) | 43.2 (10.8) | 14.5 (5.1) | 0.4 | |||
| 2 (total) | 36 | 13.9 (5.0) | 48.2 (17.0) | 8.5 (2.0) | 0.05 | 7.3 | ||
| 2 syn. | 18 | 12.1 (3.4) | 41.8 (12.9) | 12.1 (4.0) | 0.2 | |||
| 2 unsyn. | 18 | 15.6 (5.7) | 54.5 (18.6) | 8.4 (2.7) | 0.03 | |||
For Sycp3–/–, total relates to all inter-MLH1 intervals; syn. to fully synapsed inter-MLH1 intervals; and unsyn. to fully or partially unsynapsed inter-MLH1 intervals on bivalents of chromosome 1 and 2
Maximum likelihood estimate of the interference parameter ν in the gamma model (with estimated standard error s.e.)
Estimated P value; P is the probability of finding an as-bad or worse fit of the observed interfocus distances to the gamma distribution because of sampling error
v̂ corrected (corr.) for the limited range of observable interfocus distances; the correction results in slightly lower estimates of ν (cf. de Boer et al., 2006)