Comparsion of NHE3 with other human NHEs (1–9)
| . | N-terminal region (% amino acids) . | . | C-terminal region (% amino acids) . | . | ||
|---|---|---|---|---|---|---|
| . | Identical with HsNHE3 . | Positive with HsNHE3 . | Identical with HsNHE3 . | Positive with HsNHE3 . | ||
| HsNHE 1 | 47 | 65 | 21 | 36 | ||
| HsNHE 2 | 49 | 65 | 18 | 29 | ||
| HsNHE 4 | 43 | 62 | 16 | 26 | ||
| HsNHE 5 | 59 | 70 | 28 | 38 | ||
| HsNHE 6 | 27 | 42 | n.s. | n.s. | ||
| HsNHE 7 | 24 | 38 | n.s. | n.s. | ||
| HsNHE 8 | 27 | 46 | n.s. | n.s. | ||
| HsNHE 9 | 25 | 40 | n.s. | n.s. | ||
| . | N-terminal region (% amino acids) . | . | C-terminal region (% amino acids) . | . | ||
|---|---|---|---|---|---|---|
| . | Identical with HsNHE3 . | Positive with HsNHE3 . | Identical with HsNHE3 . | Positive with HsNHE3 . | ||
| HsNHE 1 | 47 | 65 | 21 | 36 | ||
| HsNHE 2 | 49 | 65 | 18 | 29 | ||
| HsNHE 4 | 43 | 62 | 16 | 26 | ||
| HsNHE 5 | 59 | 70 | 28 | 38 | ||
| HsNHE 6 | 27 | 42 | n.s. | n.s. | ||
| HsNHE 7 | 24 | 38 | n.s. | n.s. | ||
| HsNHE 8 | 27 | 46 | n.s. | n.s. | ||
| HsNHE 9 | 25 | 40 | n.s. | n.s. | ||
Comparison was done for N-terminal and C-terminal regions using Blast P(BLOSUM 62 Matrix) from http://www.ncbi.nlm.nih.gov/blast/bl2seq/wblast2.cgi. Percentage scores were calculated by dividing the number of identical and positive (conserved) amino acids by the total number of subject amino acids in HsNHE3. Sequence for all isoforms was obtained from Uniprot database http://www.uniprot.org/uniprot/
n.s., not significant