. | Mean (min) . | s.d. . | s.e.m. . | No. of bouts/worms . | P-values . |
---|---|---|---|---|---|
Swimming bout | |||||
Wild-type | 14.1 | 10.29 | 0.5 | 419/74 | n.a. |
unc-25(sa94ts) | 4.1 | 4.62 | 0.3 | 308/24 | <0.001 |
unc-25(e156) | 13.0 | 13.44 | 1.1 | 152/20 | >0.05 n.s. |
unc-30(e318) | 8.8 | 14.13 | 0.8 | 279/24 | <0.001 |
0.01 mmol l–1 aldicarb | 3.9 | 3.89 | 0.2 | 246/23 | <0.001 |
0.1 mmol l–1 aldicarb | 4.2 | 3.98 | 0.6 | 52/20 | <0.001 |
ace-1(g72);ace-2(p1000) | 8.1 | 6.79 | 0.4 | 278/25 | <0.001 |
dgk-1(nu62) | 4.1 | 3.44 | 0.1 | 433/23 | <0.001 |
glr-1::ICE(kyls36) | 5.2 | 9.38 | 0.4 | 508/29 | <0.0001 |
nmr-1::ICE(akls11) | 16.4 | 17.00 | 0.9 | 343/65 | =0.99 n.s. |
Mock ablation (glr-1::GFP) | 13.1 | 9.59 | 1.1 | 77/12 | n.a. |
AVB ablated | 5.8 | 4.17 | 0.3 | 206/16 | <0.0001* |
glr-1::GLR-1(A/T) | 10.1 | 7.93 | 0.6 | 152/30 | <0.0001 |
nmr-1::GLR-1(A/T) | 12.7 | 11.89 | 0.5 | 470/67 | <0.0001 |
egl-4(ks60) | 9.0 | 11.37 | 0.9 | 141/24 | <0.001 |
egl-4(ks61) | 4.9 | 3.34 | 0.2 | 196/24 | <0.001 |
egl-4(ks62) | 9.9 | 11.98 | 0.7 | 292/46 | <0.001 |
egl-4(n477) | 8.6 | 9.19 | 0.8 | 144/22 | <0.001 |
Quiescent bout | |||||
Wild-type | 4.8 | 2.17 | 0.1 | 489/74 | n.a. |
unc-25(sa94ts) | 9.6 | 11.71 | 0.7 | 309/24 | <0.001 |
unc-25(e156) | 8.5 | 7.58 | 0.6 | 159/20 | <0.001 |
unc-30(e318) | 8.6 | 9.09 | 0.5 | 292/24 | <0.001 |
0.01 mmol l–1 aldicarb | 10.4 | 12.59 | 0.8 | 250/23 | <0.001 |
0.1 mmol l–1 aldicarb | 29.3 | 42.18 | 4.9 | 74/20 | <0.001 |
ace-1(g72);ace2(–1000) | 10.2 | 13.07 | 0.8 | 287/25 | <0.001 |
dgk-1(nu62) | 7.2 | 6.71 | 0.3 | 436/23 | <0.001 |
glr-1::ICE(kyls36) | 7.3 | 14.64 | 0.7 | 491/29 | <0.0001 |
nmr-1::ICE(akls11) | 5.6 | 6.89 | 0.4 | 349/65 | =0.1 n.s. |
Mock ablation (glr-1::GFP) | 7.3 | 3.02 | 0.3 | 86/12 | n.a. |
AVB ablated | 9.2 | 10.29 | 0.7 | 213/16 | >0.05 n.s.* |
glr-1::GLR-1(A/T) | 25.9 | 29.84 | 2.4 | 158/30 | <0.0001 |
nmr-1::GLR-1(A/T) | 7.4 | 7.92 | 0.3 | 520/67 | =0.0006 |
egl-4(ks60) | 2.7 | 2.49 | 0.2 | 173/24 | <0.001 |
egl-4(ks61) | 2.2 | 0.96 | 0.1 | 216/24 | <0.001 |
egl-4(ks62) | 2.9 | 3.28 | 0.2 | 330/46 | <0.001 |
egl-4(n477) | 2.8 | 2.01 | 0.2 | 162/22 | <0.001 |
. | Mean (min) . | s.d. . | s.e.m. . | No. of bouts/worms . | P-values . |
---|---|---|---|---|---|
Swimming bout | |||||
Wild-type | 14.1 | 10.29 | 0.5 | 419/74 | n.a. |
unc-25(sa94ts) | 4.1 | 4.62 | 0.3 | 308/24 | <0.001 |
unc-25(e156) | 13.0 | 13.44 | 1.1 | 152/20 | >0.05 n.s. |
unc-30(e318) | 8.8 | 14.13 | 0.8 | 279/24 | <0.001 |
0.01 mmol l–1 aldicarb | 3.9 | 3.89 | 0.2 | 246/23 | <0.001 |
0.1 mmol l–1 aldicarb | 4.2 | 3.98 | 0.6 | 52/20 | <0.001 |
ace-1(g72);ace-2(p1000) | 8.1 | 6.79 | 0.4 | 278/25 | <0.001 |
dgk-1(nu62) | 4.1 | 3.44 | 0.1 | 433/23 | <0.001 |
glr-1::ICE(kyls36) | 5.2 | 9.38 | 0.4 | 508/29 | <0.0001 |
nmr-1::ICE(akls11) | 16.4 | 17.00 | 0.9 | 343/65 | =0.99 n.s. |
Mock ablation (glr-1::GFP) | 13.1 | 9.59 | 1.1 | 77/12 | n.a. |
AVB ablated | 5.8 | 4.17 | 0.3 | 206/16 | <0.0001* |
glr-1::GLR-1(A/T) | 10.1 | 7.93 | 0.6 | 152/30 | <0.0001 |
nmr-1::GLR-1(A/T) | 12.7 | 11.89 | 0.5 | 470/67 | <0.0001 |
egl-4(ks60) | 9.0 | 11.37 | 0.9 | 141/24 | <0.001 |
egl-4(ks61) | 4.9 | 3.34 | 0.2 | 196/24 | <0.001 |
egl-4(ks62) | 9.9 | 11.98 | 0.7 | 292/46 | <0.001 |
egl-4(n477) | 8.6 | 9.19 | 0.8 | 144/22 | <0.001 |
Quiescent bout | |||||
Wild-type | 4.8 | 2.17 | 0.1 | 489/74 | n.a. |
unc-25(sa94ts) | 9.6 | 11.71 | 0.7 | 309/24 | <0.001 |
unc-25(e156) | 8.5 | 7.58 | 0.6 | 159/20 | <0.001 |
unc-30(e318) | 8.6 | 9.09 | 0.5 | 292/24 | <0.001 |
0.01 mmol l–1 aldicarb | 10.4 | 12.59 | 0.8 | 250/23 | <0.001 |
0.1 mmol l–1 aldicarb | 29.3 | 42.18 | 4.9 | 74/20 | <0.001 |
ace-1(g72);ace2(–1000) | 10.2 | 13.07 | 0.8 | 287/25 | <0.001 |
dgk-1(nu62) | 7.2 | 6.71 | 0.3 | 436/23 | <0.001 |
glr-1::ICE(kyls36) | 7.3 | 14.64 | 0.7 | 491/29 | <0.0001 |
nmr-1::ICE(akls11) | 5.6 | 6.89 | 0.4 | 349/65 | =0.1 n.s. |
Mock ablation (glr-1::GFP) | 7.3 | 3.02 | 0.3 | 86/12 | n.a. |
AVB ablated | 9.2 | 10.29 | 0.7 | 213/16 | >0.05 n.s.* |
glr-1::GLR-1(A/T) | 25.9 | 29.84 | 2.4 | 158/30 | <0.0001 |
nmr-1::GLR-1(A/T) | 7.4 | 7.92 | 0.3 | 520/67 | =0.0006 |
egl-4(ks60) | 2.7 | 2.49 | 0.2 | 173/24 | <0.001 |
egl-4(ks61) | 2.2 | 0.96 | 0.1 | 216/24 | <0.001 |
egl-4(ks62) | 2.9 | 3.28 | 0.2 | 330/46 | <0.001 |
egl-4(n477) | 2.8 | 2.01 | 0.2 | 162/22 | <0.001 |
P-values are for comparison with wild-type or mock ablation(*)
n.s., non-significant difference; n.a., not applicable