Table 2.

Body mass, estradiol (E2) and bone growth

   Body mass (kg)
 		    Bone added (mm2/Mb0.66)
 		   
 
 		N
 		Initial
 		 Final
 		[E2] (pg ml-1)
 		 Femur
 		Tibia
 		 Metatarsal
 
Pooled by exercise            
    Sedentary  16 24.37±2.86  32.14±5.85 21.14±28.10  2.14±0.45 1.36±0.82*  0.91±0.53 
    Exercised  16 21.92±1.90  31.33±3.44 16.92±23.22  2.73±0.74 1.99±0.45*  1.23±0.30 
Pooled by hormone            
    Low E2  12 22.12±0.15  28.72±1.08 5.53±3.25  1.84±0.12* 1.19±0.42*  0.82±0.12* 
    Normal E2  8 25.60±2.76  37.06±2.49 2.98±1.15  2.77±0.18* 2.32±0.01*  1.51±0.01*,† 
    High E2
 
 		12
 		21.72±2.58
 		 29.43±0.32
 		48.58±6.85
 		 2.70±0.93
 		1.53±0.90
 		 0.89±0.56†
 
   Body mass (kg)
 		  Bone added (mm2/Mb0.66)
 		  Residual of bone added vs Mb
 		  
 
 		N
 		Initial
 		Final
 		[E2] (pg ml-1)
 		Femur
 		Tibia
 		Metatarsal
 		Femur
 		Tibia
 		Metatarsal
 
Sedentary            
    Low E2 (LS) 6 22.01±1.27 27.95±2.75 7.83±2.31a 1.75±0.43a 0.89±0.41a,b 0.73±0.27b -3.57±2.44a -3.78±1.60a,b -1.1±1.47 
    Normal E2 (NS) 4 27.55±1.54a 38.82±2.29a 2.16±0.46a 2.64±0.32 2.31±0.13 1.51±0.24 -3.34±4.09a 0.15±1.62 0.64±3.22 
    High E2 (HS) 6 23.54±1.54 29.65±3.52 53.42±11.27 2.04±0.36a 0.89±0.37a,b 0.49±0.17a,b -2.03±1.58a -5.12±2.73a,b -4.10±0.78a,b 
Exercised            
    Low E2 (LE) 6 22.22±2.36 29.48±3.91 3.23±0.40a 1.92±0.47a 1.48±0.43 0.90±0.31 -2.35±2.87a 0.85±2.35 0.04±1.73 
    Normal E2 (NE) 4 23.65±0.74 35.30±2.06 3.79±0.40a 2.90±0.42 2.32±0.15b 1.50±0.21b 2.06±3.82 2.97±1.66b 2.33±2.09b 
    High E2 (HE) 6 19.89±1.59a 29.20±2.42a 43.73±5.13a 3.36±0.38a 2.16±0.22a 1.28±0.13a 8.80±2.93a 5.97±2.01a 2.80±1.41a 
   Body mass (kg)
 		    Bone added (mm2/Mb0.66)
 		   
 
 		N
 		Initial
 		 Final
 		[E2] (pg ml-1)
 		 Femur
 		Tibia
 		 Metatarsal
 
Pooled by exercise            
    Sedentary  16 24.37±2.86  32.14±5.85 21.14±28.10  2.14±0.45 1.36±0.82*  0.91±0.53 
    Exercised  16 21.92±1.90  31.33±3.44 16.92±23.22  2.73±0.74 1.99±0.45*  1.23±0.30 
Pooled by hormone            
    Low E2  12 22.12±0.15  28.72±1.08 5.53±3.25  1.84±0.12* 1.19±0.42*  0.82±0.12* 
    Normal E2  8 25.60±2.76  37.06±2.49 2.98±1.15  2.77±0.18* 2.32±0.01*  1.51±0.01*,† 
    High E2
 
 		12
 		21.72±2.58
 		 29.43±0.32
 		48.58±6.85
 		 2.70±0.93
 		1.53±0.90
 		 0.89±0.56†
 
   Body mass (kg)
 		  Bone added (mm2/Mb0.66)
 		  Residual of bone added vs Mb
 		  
 
 		N
 		Initial
 		Final
 		[E2] (pg ml-1)
 		Femur
 		Tibia
 		Metatarsal
 		Femur
 		Tibia
 		Metatarsal
 
Sedentary            
    Low E2 (LS) 6 22.01±1.27 27.95±2.75 7.83±2.31a 1.75±0.43a 0.89±0.41a,b 0.73±0.27b -3.57±2.44a -3.78±1.60a,b -1.1±1.47 
    Normal E2 (NS) 4 27.55±1.54a 38.82±2.29a 2.16±0.46a 2.64±0.32 2.31±0.13 1.51±0.24 -3.34±4.09a 0.15±1.62 0.64±3.22 
    High E2 (HS) 6 23.54±1.54 29.65±3.52 53.42±11.27 2.04±0.36a 0.89±0.37a,b 0.49±0.17a,b -2.03±1.58a -5.12±2.73a,b -4.10±0.78a,b 
Exercised            
    Low E2 (LE) 6 22.22±2.36 29.48±3.91 3.23±0.40a 1.92±0.47a 1.48±0.43 0.90±0.31 -2.35±2.87a 0.85±2.35 0.04±1.73 
    Normal E2 (NE) 4 23.65±0.74 35.30±2.06 3.79±0.40a 2.90±0.42 2.32±0.15b 1.50±0.21b 2.06±3.82 2.97±1.66b 2.33±2.09b 
    High E2 (HE) 6 19.89±1.59a 29.20±2.42a 43.73±5.13a 3.36±0.38a 2.16±0.22a 1.28±0.13a 8.80±2.93a 5.97±2.01a 2.80±1.41a 

Values are means ± 1 s.e.m.

Symbols indicate significant differences between pairs; letters indicate significant difference with aHE or bNE (P<0.05, ANOVA, Fisher's LSD).

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