. | Baseline . | . | Maximal workload . | . | P values . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | C (N=8) . | S (N=8) . | C (N=8) . | S (N=8) . | d.f. . | Line . | Treatment . | Power of analysis . | ||||
Wheel-running activity (km day-1) | 11.5±1.2 | 14.7±0.8 | 23.2±1.4 | 23.4±1.4 | 1,14 | 0.29 | <0.001 | 0.22/0.24 | ||||
Body mass (g) | 30.9±0.5 | 30.6±0.5 | 26.0±0.3 | 25.5±0.5 | 1,14 | 0.82 | <0.001 | 0.98/0.99 | ||||
Food intake (g day-1) | 5.7±0.1 | 6.0±0.2 | 4.6±0.3 | 4.6±0.2 | 1,14 | 0.44 | <0.001 | 0.52/0.17 | ||||
Mass-specific food intake (g g-1 day-1) | 0.20±0.01 | 1 | 0.18±0.01 | 0.18±0.01 | 1,14 | 0.38 | 0.43 | 0.96/0.54 |
. | Baseline . | . | Maximal workload . | . | P values . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | C (N=8) . | S (N=8) . | C (N=8) . | S (N=8) . | d.f. . | Line . | Treatment . | Power of analysis . | ||||
Wheel-running activity (km day-1) | 11.5±1.2 | 14.7±0.8 | 23.2±1.4 | 23.4±1.4 | 1,14 | 0.29 | <0.001 | 0.22/0.24 | ||||
Body mass (g) | 30.9±0.5 | 30.6±0.5 | 26.0±0.3 | 25.5±0.5 | 1,14 | 0.82 | <0.001 | 0.98/0.99 | ||||
Food intake (g day-1) | 5.7±0.1 | 6.0±0.2 | 4.6±0.3 | 4.6±0.2 | 1,14 | 0.44 | <0.001 | 0.52/0.17 | ||||
Mass-specific food intake (g g-1 day-1) | 0.20±0.01 | 1 | 0.18±0.01 | 0.18±0.01 | 1,14 | 0.38 | 0.43 | 0.96/0.54 |
Wheel-running activity, body mass and food intake during baseline and at maximal workload in activity-selected mice and random-bred controls. Values given are mean ± s.e.m. Repeated-measures ANOVA with line (C versus S) as between-subjects factor and treatment (baseline versus workload) as within-subjects factor were performed. Interactions between line and treatment was never significant and are therefore not shown in the Table. Significant results are highlighted in bold
d.f., degrees of freedom; N, sample size
A power analysis for the two-tailed t-tests was performed at a fixed effect size of 10% difference between the lines using the Gpower program(Faul and Erdfelder, 1992); we entered mean values and s.e.m. measured for control mice and calculated the power when the mean for the selected mice differed from the controls by 10%. The values in the Table represent the power for the comparison between C and S mice at baseline and workload, respectively