Resting heart rate and input pressure, and maximum cardiac performance of GH transgenic and control Atlantic salmon in situ hearts
| . | Control . | Transgenic . | Trans/Con ratio . | P value . |
|---|---|---|---|---|
| Resting | ||||
| Pin (kPa) | -0.15±0.060 | -0.001±0.025 | 0.64 | 0.35 |
| Heart rate (beats min-1) | 73±2 | 84±3 | 1.14 | 0.007* |
| Parameters at maximum cardiac output | ||||
| Q̇ (ml min-1 kg-1) | 63.8±1.9 | 75.5±2.8 | 1.18 | 0.005* |
| VS (ml kg-1) | 0.93±0.03 | 1.03±0.05 | 1.11 | 0.16 |
| Heart rate (beats min-1) | 69±1 | 74±2 | 1.07 | 0.04* |
| Q̇ (ml min-1 g-1 ventricle) | 96.0±4.4 | 95.7±1.9 | 0.99 | 0.95 |
| VS (ml g vent-1) | 1.4±0.09 | 1.3±0.04 | 0.94 | 0.28 |
| Power (mW g-1 ventricle) | 9.69±0.41 | 9.67±0.5 | 0.99 | 0.98 |
| . | Control . | Transgenic . | Trans/Con ratio . | P value . |
|---|---|---|---|---|
| Resting | ||||
| Pin (kPa) | -0.15±0.060 | -0.001±0.025 | 0.64 | 0.35 |
| Heart rate (beats min-1) | 73±2 | 84±3 | 1.14 | 0.007* |
| Parameters at maximum cardiac output | ||||
| Q̇ (ml min-1 kg-1) | 63.8±1.9 | 75.5±2.8 | 1.18 | 0.005* |
| VS (ml kg-1) | 0.93±0.03 | 1.03±0.05 | 1.11 | 0.16 |
| Heart rate (beats min-1) | 69±1 | 74±2 | 1.07 | 0.04* |
| Q̇ (ml min-1 g-1 ventricle) | 96.0±4.4 | 95.7±1.9 | 0.99 | 0.95 |
| VS (ml g vent-1) | 1.4±0.09 | 1.3±0.04 | 0.94 | 0.28 |
| Power (mW g-1 ventricle) | 9.69±0.41 | 9.67±0.5 | 0.99 | 0.98 |
Resting Pin was set to achieve a physiological resting cardiac output of approximately 16 ml min-1 kg-1.
Values are means ± 1 standard error (control, N=8;transgenic, N=7).
Significant difference (P<0.05) between groups.