Summary of the effect of long-day photoperiod (LD) on gene expression of hypothalamic neuropeptide and receptor systems in bank voles and Siberian hamsters
| Neuropeptide/receptor . | Bank voles . | Siberian hamstersa . | Siberian hamstersb . |
|---|---|---|---|
| NPY (ARC) | ↔ | ↔ | ↔ |
| AGRP (ARC) | ↔ | ↔ | — |
| POMC (ARC) | ↑c | ↑ | ↑ |
| CART (ARC) | ↔ | ↓ | — |
| CRF (PVN) | ↑ | ↑ | — |
| MC3-R (ARC) | ↑ | ↑ | — |
| MC3-R (VMN) | ↔ | ↓ | — |
| MC4-R (PVN) | ↔ | ↔ | — |
| Neuropeptide/receptor . | Bank voles . | Siberian hamstersa . | Siberian hamstersb . |
|---|---|---|---|
| NPY (ARC) | ↔ | ↔ | ↔ |
| AGRP (ARC) | ↔ | ↔ | — |
| POMC (ARC) | ↑c | ↑ | ↑ |
| CART (ARC) | ↔ | ↓ | — |
| CRF (PVN) | ↑ | ↑ | — |
| MC3-R (ARC) | ↑ | ↑ | — |
| MC3-R (VMN) | ↔ | ↓ | — |
| MC4-R (PVN) | ↔ | ↔ | — |
Arrows indicate the lack of change (↔), elevated (↑) or reduced(↓) gene expression relative to short-day photoperiod (SD) individuals. Data for Siberian hamsters were originally presented as gene expression for SD individuals relative to LD individuals.
NPY, neuropeptide Y; ARC, arcuate nucleus; AGRP, agouti-related protein;POMC, pro-opiomelanocortin; CART, cocaine- and amphetamine-regulated transcript; CRF, corticotrophin-releasing factor; PVN, paraventricular nucleus; MC3-R and MC4-R, melanocortin-3 and -4 receptors; VMN, ventromedial nucleus.
Mercer et al., 2001;
Reddy et al., 1999;
the difference approached significance at P=0.06