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Table 2.

Kinetics of restoration of blood volume following 20% or 35% reduction of blood volume

Blood volume (ml kg-1)
Half-time (min)
Hemorrhage (%)Initial HctRecovered at 5 minaRecovered at 60 minaEquilibriumbkr2
20 (N=9) 26.1±2.8 6.8±1.5 13.4±2.0 41.7 0.052 13.3 0.98 
35 (N=6) 27.2±3.1 8.5±0.6 18.2±1.5 41.3 0.046 15.1 0.97 
Blood volume (ml kg-1)
Half-time (min)
Hemorrhage (%)Initial HctRecovered at 5 minaRecovered at 60 minaEquilibriumbkr2
20 (N=9) 26.1±2.8 6.8±1.5 13.4±2.0 41.7 0.052 13.3 0.98 
35 (N=6) 27.2±3.1 8.5±0.6 18.2±1.5 41.3 0.046 15.1 0.97 

20% hemorrhage=7 ml kg-1 removed, 35% hemorrhage=12.3 ml kg-1 removed.

k, rate constant; r2, from mono-exponential curve-fit.

Values are means ± S.E.M., N = number of fish.

a

Estimated fluid volume returned to vasculature based on change in hematocrit.

b

Predicted final blood volume after fluid influx into vasculature has ceased(calculated from the exponential recovery curve; Equation 3).

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