Kinetics of restoration of blood volume following 20% or 35% reduction of blood volume
| . | . | Blood volume (ml kg-1) . | . | . | . | Half-time (min) . | . | ||
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage (%) . | Initial Hct . | Recovered at 5 mina . | Recovered at 60 mina . | Equilibriumb . | k . | . | r2 . | ||
| 20 (N=9) | 26.1±2.8 | 6.8±1.5 | 13.4±2.0 | 41.7 | 0.052 | 13.3 | 0.98 | ||
| 35 (N=6) | 27.2±3.1 | 8.5±0.6 | 18.2±1.5 | 41.3 | 0.046 | 15.1 | 0.97 | ||
| . | . | Blood volume (ml kg-1) . | . | . | . | Half-time (min) . | . | ||
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhage (%) . | Initial Hct . | Recovered at 5 mina . | Recovered at 60 mina . | Equilibriumb . | k . | . | r2 . | ||
| 20 (N=9) | 26.1±2.8 | 6.8±1.5 | 13.4±2.0 | 41.7 | 0.052 | 13.3 | 0.98 | ||
| 35 (N=6) | 27.2±3.1 | 8.5±0.6 | 18.2±1.5 | 41.3 | 0.046 | 15.1 | 0.97 | ||
20% hemorrhage=7 ml kg-1 removed, 35% hemorrhage=12.3 ml kg-1 removed.
k, rate constant; r2, from mono-exponential curve-fit.
Values are means ± S.E.M., N = number of fish.
Estimated fluid volume returned to vasculature based on change in hematocrit.
Predicted final blood volume after fluid influx into vasculature has ceased(calculated from the exponential recovery curve; Equation 3).