Effects of forskolin, theophylline and db-cAMP on bioelectrical parameters across the duodenal mucosa of Gallotia galloti
| . | PD (mV) . | Isc (μequiv. cm-2 h-1) . | Gt (mS cm-2) . |
|---|---|---|---|
| Control | 2.01±0.2 | 1.01±0.15 | 7.95±1.1 |
| Forskolin | 2.80±0.2** | 1.50±0.2* | 8.95±1.2 |
| (10 μmol l-1) | |||
| (16) | |||
| Control | 2.3±0.2 | 0.70±0.15 | 8.01±0.6 |
| Theophylline | 2.8±0.2* | 1.15±0.18* | 8.05±0.5 |
| (3 mmol l-1) | |||
| (12) | |||
| Control | 2.60±0.2 | 0.60±0.1 | 8.01±0.8 |
| db-cAMP | 3.05±0.1* | 0.95±0.1* | 8.01±0.5 |
| (500 μmol l-1) | |||
| (8) |
| . | PD (mV) . | Isc (μequiv. cm-2 h-1) . | Gt (mS cm-2) . |
|---|---|---|---|
| Control | 2.01±0.2 | 1.01±0.15 | 7.95±1.1 |
| Forskolin | 2.80±0.2** | 1.50±0.2* | 8.95±1.2 |
| (10 μmol l-1) | |||
| (16) | |||
| Control | 2.3±0.2 | 0.70±0.15 | 8.01±0.6 |
| Theophylline | 2.8±0.2* | 1.15±0.18* | 8.05±0.5 |
| (3 mmol l-1) | |||
| (12) | |||
| Control | 2.60±0.2 | 0.60±0.1 | 8.01±0.8 |
| db-cAMP | 3.05±0.1* | 0.95±0.1* | 8.01±0.5 |
| (500 μmol l-1) | |||
| (8) |
Number of experiments for each experimental condition indicated in parentheses. *P<0.05; **P<0.01 compared with control tissues.
db-cAMP, dibutyryl cAMP; PD, potential difference; Isc,short-circuit current; Gt, tissue conductance.