Citrate synthase (CS), β-hydroxyacyl-CoA dehydrogenase (HOAD) and lactate dehydrogenase (LDH) activities scaled to tissue-specific resting metabolic rate (RMR) for harbor seals, dogs and rats
| Species . | Mass (kg) . | N . | Organ . | CS/RMR . | HOAD/RMR . | LDH/RMR . |
|---|---|---|---|---|---|---|
| Harbor seals | 46.1±4.3 | 10 | Heart | 3.1×10-2±2.3×10-3 | 4.2×10-2±1.7×10-3α,δ | 2.9×10-1±9.8×10-3α |
| 8 | Liver | 1.3×10-2±4.9×10-4α,δ | 1.1×10-2±6.1×10-4α,δ | 1.1±6.6×10-2α,δ | ||
| 10 | Kidney | 7.2×10-3±1.7×10-4 | 1.1×10-1±2.1×10-2 | 8.8×10-2±2.7×10-3α | ||
| 10 | Stomach | 1.7×10-1±2.8×10-2 | 6.6×10-2±1.0×10-2 | 2.4±2.3×10-1δ | ||
| 9 | Intestine | 2.4×10-3 | 5.1×10-2±4.6×10-3α | 3.8±1.9×10-1α,δ | ||
| Dogs | 9.2±0.5 | 3 | Heart | 2.5×10-2±8.9×10-4 | 1.3×10-2±2.6×10-3 | 1.9×10-1±1.6×10-2 |
| 3 | Liver | 5.2×10-3±2.4×10-4 | 1.3×10-3±9.0×10-5 | 2.0×10-1±1.2×10-2 | ||
| 3 | Kidney | 8.8×10-3±2.6×10-4ω | 7.0×10-2±2.7×10-2 | 8.6×10-2±8.4×10-3 | ||
| 3 | Stomach | 2.5×10-1±5.1×10-2 | 4.8×10-2±9.7×10-3 | 2.4±2.0×10-1 | ||
| 3 | Intestine | 1.6×10-3 | 2.8×10-2±2.5×10-3 | 1.6±5.0×10-3 | ||
| Rats | 0.48±0.03 | 3 | Heart | 3.1×10-2±2.1×10-3 | 6.8×10-3±2.8×10-4 | 3.3×10-1±1.8×10-2α |
| 3 | Liver | 3.5×10-3±1.7×10-4 | 2.0×10-3±1.3×10-4 | 2.3×10-1±5.9×10-3 | ||
| 1 | Kidney | 6.2×10-3 | 4.7×10-2 | 3.3×10-2 | ||
| 3 | Stomach | 1.2×10-1±3.5×10-2 | 4.8×10-2±1.0×10-2 | 1.2±7.4×10-2 | ||
| 3 | Intestine | 1.6×10-3 | 4.2×10-2±5.2×10-3 | 1.9±2.1×10-2 |
| Species . | Mass (kg) . | N . | Organ . | CS/RMR . | HOAD/RMR . | LDH/RMR . |
|---|---|---|---|---|---|---|
| Harbor seals | 46.1±4.3 | 10 | Heart | 3.1×10-2±2.3×10-3 | 4.2×10-2±1.7×10-3α,δ | 2.9×10-1±9.8×10-3α |
| 8 | Liver | 1.3×10-2±4.9×10-4α,δ | 1.1×10-2±6.1×10-4α,δ | 1.1±6.6×10-2α,δ | ||
| 10 | Kidney | 7.2×10-3±1.7×10-4 | 1.1×10-1±2.1×10-2 | 8.8×10-2±2.7×10-3α | ||
| 10 | Stomach | 1.7×10-1±2.8×10-2 | 6.6×10-2±1.0×10-2 | 2.4±2.3×10-1δ | ||
| 9 | Intestine | 2.4×10-3 | 5.1×10-2±4.6×10-3α | 3.8±1.9×10-1α,δ | ||
| Dogs | 9.2±0.5 | 3 | Heart | 2.5×10-2±8.9×10-4 | 1.3×10-2±2.6×10-3 | 1.9×10-1±1.6×10-2 |
| 3 | Liver | 5.2×10-3±2.4×10-4 | 1.3×10-3±9.0×10-5 | 2.0×10-1±1.2×10-2 | ||
| 3 | Kidney | 8.8×10-3±2.6×10-4ω | 7.0×10-2±2.7×10-2 | 8.6×10-2±8.4×10-3 | ||
| 3 | Stomach | 2.5×10-1±5.1×10-2 | 4.8×10-2±9.7×10-3 | 2.4±2.0×10-1 | ||
| 3 | Intestine | 1.6×10-3 | 2.8×10-2±2.5×10-3 | 1.6±5.0×10-3 | ||
| Rats | 0.48±0.03 | 3 | Heart | 3.1×10-2±2.1×10-3 | 6.8×10-3±2.8×10-4 | 3.3×10-1±1.8×10-2α |
| 3 | Liver | 3.5×10-3±1.7×10-4 | 2.0×10-3±1.3×10-4 | 2.3×10-1±5.9×10-3 | ||
| 1 | Kidney | 6.2×10-3 | 4.7×10-2 | 3.3×10-2 | ||
| 3 | Stomach | 1.2×10-1±3.5×10-2 | 4.8×10-2±1.0×10-2 | 1.2±7.4×10-2 | ||
| 3 | Intestine | 1.6×10-3 | 4.2×10-2±5.2×10-3 | 1.9±2.1×10-2 |
Values are means ± s.e.m. (N = no. of animals). αSignificantly different from dog (ANOVA, P<0.05); δsignificantly different from rat(ANOVA, P<0.05); ωsignificantly different from harbor seal (ANOVA, P<0.05). Values with no s.e.m. were not included in the analysis and are presented for comparison. RMR for specific tissues was calculated as in Table 4.