Effects of hypoxia and anaemia on arterial blood gases and haematological parameters in Bufo marinus
| Haematocrit FIO2 . | Normal 0.21 . | Normal 0.10 . | Anaemic 0.21 . | Significance . |
|---|---|---|---|---|
| [O2] (mmol l-1) | 2.39±0.28 | 1.47±0.21 | 1.41±0.22 | a,b |
| PaO2 (mm Hg) | 68.5±7.0 | 38.2±3.6 | 59.7±8.3 | a,c |
| HbO2sat | 0.80±0.05 | 0.47±0.06 | 0.82±0.07 | a,c |
| Haematocrit | 0.20±0.03 | 0.20±0.03 | 0.11±0.01 | b,c |
| [Hb4] (mmol l-1) | 0.73±0.10 | 0.80±0.11 | 0.41±0.05 | b,c |
| MCHC | 4.05±0.11 | 4.12±0.20 | 4.00±0.12 | |
| Plasma pH | 7.74±0.03 | 7.88±0.02 | 7.74±0.02 | a,c |
| PaCO2 (mm Hg) | 15.6±1.2 | 10.6±0.5 | 16.2±1.7 | a,c |
| [HCO3-] (mmol l-1) | 26.6±1.8 | 26.1±1.6 | 27.2±2.1 |
| Haematocrit FIO2 . | Normal 0.21 . | Normal 0.10 . | Anaemic 0.21 . | Significance . |
|---|---|---|---|---|
| [O2] (mmol l-1) | 2.39±0.28 | 1.47±0.21 | 1.41±0.22 | a,b |
| PaO2 (mm Hg) | 68.5±7.0 | 38.2±3.6 | 59.7±8.3 | a,c |
| HbO2sat | 0.80±0.05 | 0.47±0.06 | 0.82±0.07 | a,c |
| Haematocrit | 0.20±0.03 | 0.20±0.03 | 0.11±0.01 | b,c |
| [Hb4] (mmol l-1) | 0.73±0.10 | 0.80±0.11 | 0.41±0.05 | b,c |
| MCHC | 4.05±0.11 | 4.12±0.20 | 4.00±0.12 | |
| Plasma pH | 7.74±0.03 | 7.88±0.02 | 7.74±0.02 | a,c |
| PaCO2 (mm Hg) | 15.6±1.2 | 10.6±0.5 | 16.2±1.7 | a,c |
| [HCO3-] (mmol l-1) | 26.6±1.8 | 26.1±1.6 | 27.2±2.1 |
Fraction of inspired oxygen (FIO2), oxygen concentration ([O2]), oxygen tension(PaO2), haemoglobin oxygen saturation(HbO2sat), haemoglobin concentration ([Hb4]), mean cellular haemoglobin concentration (MCHC), plasma carbon dioxide tension(PaCO2) and bicarbonate concentration([HCO3-]).
Values are means ± 1 S.E.M. 1 mm Hg=133.3 Pa.
denotes a significant difference between normal normoxia and normal hypoxia; `b' denotes a significant difference between normal normoxia and anaemia and `c' denotes a significant difference between normal hypoxia and anaemia.