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Table 2.

Effects of the injection of an antisense morpholino oligonucleotide against mezzo (mezzo-MO) in several mutants of the Nodal signalling pathway

Uninjected
Embryos injected with 24 ng of mezzo-MO
Mutant backgroundNumber of embryos with mutant phenotypenPercentage of embryos with mutant phenotypeNumber of embryos with mutant phenotypenPercentage of embryos with mutant phenotype
one eyed pinhead 12 50 24 11 43 26 
squint 43 19 96 20 
MZsquint 15 25 60 33 33 100 
faust 35 20 40 23 
casanova 13 62 21 26 23 
Uninjected
Embryos injected with 24 ng of mezzo-MO
Mutant backgroundNumber of embryos with mutant phenotypenPercentage of embryos with mutant phenotypeNumber of embryos with mutant phenotypenPercentage of embryos with mutant phenotype
one eyed pinhead 12 50 24 11 43 26 
squint 43 19 96 20 
MZsquint 15 25 60 33 33 100 
faust 35 20 40 23 
casanova 13 62 21 26 23 

mezzo-MO increases the penetrance of squint andMZsquint.

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