Table 2.

Neuronal migration speed in brain slice cultures

MigrationWild typeC3Ggt/gt mutantP value
Fast-moving cells 10.6±0.5 4.9±0.9 P<0.0001 
Slow-moving cells 4.6±0.5 2.7±0.5 P=0.0008 
All cells 7.6±0.8 3.8±0.3 P<0.0001 
MigrationWild typeC3Ggt/gt mutantP value
Fast-moving cells 10.6±0.5 4.9±0.9 P<0.0001 
Slow-moving cells 4.6±0.5 2.7±0.5 P=0.0008 
All cells 7.6±0.8 3.8±0.3 P<0.0001 

Mean speed (μm/hour) ± s.e.m. in three wild types and three C3Ggt/gt mutants were assessed. The migration speed of the 10-12 most-mobile cells was recorded per animal. Data were analysed by one-factorial ANOVA.

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