Distribution of BrdU+ cells in wild-type versus C3Ggt/gt mutant brains labelled with BrdU at E10.5 and recovered at E14.5
| Location . | Wild type . | C3Ggt/gt mutant . |
|---|---|---|
| Marginal zone | 20.7±2.9 | 29.7±3.6 |
| 52.10% | 91.28% | |
| Submarginal areas | 19.0±2.6 | 2.8±0.7* |
| 47.90% | 8.72% |
| Location . | Wild type . | C3Ggt/gt mutant . |
|---|---|---|
| Marginal zone | 20.7±2.9 | 29.7±3.6 |
| 52.10% | 91.28% | |
| Submarginal areas | 19.0±2.6 | 2.8±0.7* |
| 47.90% | 8.72% |
Shown are the number of strongly BrdU+ cells (± s.e.m.)counted at each location, also expressed as a percentage of the total. n=both hemispheres of three wild types and three C3Ggt/gt mutants.
The distribution of BrdU+ cells was significantly altered in the C3Ggt/gt mutant (P<0.0001 by X2test).
C3Ggt/gt ≠ wild type in submarginal areas, P=0.0001 by one-factorial ANOVA.