Selected genes up- or downregulated in activated β-catenin mutant epidermis at E15.5
| A. Upregulated genes | |
| Wnt/β-catenin pathway | Lef1, Tcf4, Nkd1, Nkd2, Dkk4, Dact1, Wif1, Axin2, Krm1, Wisp1, Wnt5a,Wnt11, Wnt10a |
| Non-canonical Wnt pathway | Daam2, Prickle2, Vangl2, Ror2, Wnt5a, Wnt11 |
| SHH pathway | Shh, Ptch1, Ptch2, Smo, Gli3 |
| BMP pathway | Bmp2, Bmp4, Msx1, Msx2 |
| Notch pathway | Hey1, Hes6, Deltex 1, Dll1 |
| Axon guidance | Sema4c, Sema3c, Unc5b, Unc5c |
| Neuronal | Robo1, Netrin G1 |
| Melanoblast regulatory | Adamts20, Kitl |
| Melanoblast/melanocyte expressed | Mlana, Mitf, Mc1r |
| Pigment deposition | Foxn1 |
| Hair shaft precursor associated | S100a3, Mt4, Bmp2, Bmp4, Msx1, Msx2, Hoxc13, Foxq1, Foxn1 |
| Buttonhead family transcription factors | Sp5, Sp8 |
| Hair shaft keratins | Krt31, Krt32, Krt33a, Krt34, Krt35, Krt82, Krt85, mHa3 |
| Hair shaft keratin-associated proteins | Krtap 16 family |
| Keratins specific for IRS cuticle | Krt72, Krt73, Krt26 |
| Keratins expressed in IRS cuticle and other IRS layers | Krt25, Krt27, Krt71 |
| B. Downregulated genes | |
| GATA3-regulated genes | Gata3, Ptgs1, Sgpp1 |
| Signaling molecules | Wnt7a, Tgfbr3 |
| Homeobox-containing transcription factors | Hoxa3, Hoxa5, Hoxa7, Irx1, Irx2 |
| Stem cell associated | Lrig1, Krt15 |
| Epidermal stratification | Krt14, Krt1, Krt10, Lor, Casp14, Clca1, Clca2, Hrnr |
| Desmosomal components | Dsc1, Dsc3, Dsg1 |
| A. Upregulated genes | |
| Wnt/β-catenin pathway | Lef1, Tcf4, Nkd1, Nkd2, Dkk4, Dact1, Wif1, Axin2, Krm1, Wisp1, Wnt5a,Wnt11, Wnt10a |
| Non-canonical Wnt pathway | Daam2, Prickle2, Vangl2, Ror2, Wnt5a, Wnt11 |
| SHH pathway | Shh, Ptch1, Ptch2, Smo, Gli3 |
| BMP pathway | Bmp2, Bmp4, Msx1, Msx2 |
| Notch pathway | Hey1, Hes6, Deltex 1, Dll1 |
| Axon guidance | Sema4c, Sema3c, Unc5b, Unc5c |
| Neuronal | Robo1, Netrin G1 |
| Melanoblast regulatory | Adamts20, Kitl |
| Melanoblast/melanocyte expressed | Mlana, Mitf, Mc1r |
| Pigment deposition | Foxn1 |
| Hair shaft precursor associated | S100a3, Mt4, Bmp2, Bmp4, Msx1, Msx2, Hoxc13, Foxq1, Foxn1 |
| Buttonhead family transcription factors | Sp5, Sp8 |
| Hair shaft keratins | Krt31, Krt32, Krt33a, Krt34, Krt35, Krt82, Krt85, mHa3 |
| Hair shaft keratin-associated proteins | Krtap 16 family |
| Keratins specific for IRS cuticle | Krt72, Krt73, Krt26 |
| Keratins expressed in IRS cuticle and other IRS layers | Krt25, Krt27, Krt71 |
| B. Downregulated genes | |
| GATA3-regulated genes | Gata3, Ptgs1, Sgpp1 |
| Signaling molecules | Wnt7a, Tgfbr3 |
| Homeobox-containing transcription factors | Hoxa3, Hoxa5, Hoxa7, Irx1, Irx2 |
| Stem cell associated | Lrig1, Krt15 |
| Epidermal stratification | Krt14, Krt1, Krt10, Lor, Casp14, Clca1, Clca2, Hrnr |
| Desmosomal components | Dsc1, Dsc3, Dsg1 |