Expression of laterality markers after Arhgef11 loss-of-function
| . | Embryo type . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|
| . | WT . | AUGMO . | SPLMO . | ΔDHPH . | vu7/vu7 . | ||||
| spaw in LPM (19 hpf) | |||||||||
| n | 513 | 194 | 92 | 306 | 64 | ||||
| L | 88% | 21% | 50% | 58% | 75% | ||||
| B | 10% | 5% | 21% | 15% | 23% | ||||
| R | 2% | 13% | 25% | 15% | 0% | ||||
| A | <1% | 61% | 4% | 12% | 2% | ||||
| pitx2 in LPM (21 hpf) | |||||||||
| n | 120 | 115 | - | 74 | 80 | ||||
| L | 99% | 35% | - | 87% | 85% | ||||
| B | 1% | 14% | - | 5% | 10% | ||||
| R | 0% | 29% | - | 8% | 0% | ||||
| A | 0% | 22% | - | 0% | 5% | ||||
| cmlc2 (30 hpf) | |||||||||
| n | 220 | 96 | 106 | 65 | 173 | ||||
| L | 99% | 52% | 79% | 48% | 78% | ||||
| M | 0% | 23% | 17% | 14% | 20% | ||||
| R | <1% | 25% | 4% | 0% | 2% | ||||
| T | 0% | 0% | 0% | 38% | 0% | ||||
| ins (53 hpf) | |||||||||
| n | 178 | 103 | 52 | 62 | - | ||||
| L | 2% | 29% | 8% | 8% | - | ||||
| M | 3% | 21% | 23% | 11% | - | ||||
| R | 95% | 50% | 69% | 73% | - | ||||
| T | 0% | 0% | 0% | 8% | - | ||||
| . | Embryo type . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|
| . | WT . | AUGMO . | SPLMO . | ΔDHPH . | vu7/vu7 . | ||||
| spaw in LPM (19 hpf) | |||||||||
| n | 513 | 194 | 92 | 306 | 64 | ||||
| L | 88% | 21% | 50% | 58% | 75% | ||||
| B | 10% | 5% | 21% | 15% | 23% | ||||
| R | 2% | 13% | 25% | 15% | 0% | ||||
| A | <1% | 61% | 4% | 12% | 2% | ||||
| pitx2 in LPM (21 hpf) | |||||||||
| n | 120 | 115 | - | 74 | 80 | ||||
| L | 99% | 35% | - | 87% | 85% | ||||
| B | 1% | 14% | - | 5% | 10% | ||||
| R | 0% | 29% | - | 8% | 0% | ||||
| A | 0% | 22% | - | 0% | 5% | ||||
| cmlc2 (30 hpf) | |||||||||
| n | 220 | 96 | 106 | 65 | 173 | ||||
| L | 99% | 52% | 79% | 48% | 78% | ||||
| M | 0% | 23% | 17% | 14% | 20% | ||||
| R | <1% | 25% | 4% | 0% | 2% | ||||
| T | 0% | 0% | 0% | 38% | 0% | ||||
| ins (53 hpf) | |||||||||
| n | 178 | 103 | 52 | 62 | - | ||||
| L | 2% | 29% | 8% | 8% | - | ||||
| M | 3% | 21% | 23% | 11% | - | ||||
| R | 95% | 50% | 69% | 73% | - | ||||
| T | 0% | 0% | 0% | 8% | - | ||||
n, number of embryos; L, left-sided; B, bilateral; R, right-sided;A, absent; M, medial; T, two fields.