Rescue of the placental phenotype in Sox2Cre transgene-mediated recombination
| . | Genotype of live born pups . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Map2k1+/+; Tg+/+ . | Map2k1+/Δ; Tg+/+ . | Map2k1floxed/Δ; Tg+/+ . | Map2k1+/floxed; Tg+/+ . | Map2k1+/+; Tg+/Sox2Cre . | Map2k1+/Δ; Tg+/Sox2Cre . | Map2k1Δ/Δ; Tg+/Sox2Cre . | ||||||
| Number of pups | 6 | 8 | 4 | 4 | 6 | 6 | 6 | ||||||
| % obtained | 15% | 20% | 10% | 10% | 15% | 15% | 15% | ||||||
| % expected | 12.5% | 12.5% | 12.5% | 12.5% | 12.5% | 25% | 12.5% | ||||||
| . | Genotype of live born pups . | . | . | . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Map2k1+/+; Tg+/+ . | Map2k1+/Δ; Tg+/+ . | Map2k1floxed/Δ; Tg+/+ . | Map2k1+/floxed; Tg+/+ . | Map2k1+/+; Tg+/Sox2Cre . | Map2k1+/Δ; Tg+/Sox2Cre . | Map2k1Δ/Δ; Tg+/Sox2Cre . | ||||||
| Number of pups | 6 | 8 | 4 | 4 | 6 | 6 | 6 | ||||||
| % obtained | 15% | 20% | 10% | 10% | 15% | 15% | 15% | ||||||
| % expected | 12.5% | 12.5% | 12.5% | 12.5% | 12.5% | 25% | 12.5% | ||||||
Male Map2k1+/Δ;Tg+/Sox2Crewere crossed with female Map2k1+/floxed