FGF/ERK signalling negatively regulates the activity of Casanova at the animal pole
| RNA injected at the 16-cell stage . | Casanova-WT . | Casanova-S47A . | Casanova-WT + SU5402 . | Casanova-WT + Mkp3 . | Casanova-WT + Erk2* . | Casanova-S47A + Erk2* . |
|---|---|---|---|---|---|---|
| % Embryos showing ectopic sox17 expression | 30 | 46 | 49 | 64 | 3 | 54 |
| Total number of embryos | 381 | 214 | 182 | 205 | 167 | 118 |
| RNA injected at the 16-cell stage . | Casanova-WT . | Casanova-S47A . | Casanova-WT + SU5402 . | Casanova-WT + Mkp3 . | Casanova-WT + Erk2* . | Casanova-S47A + Erk2* . |
|---|---|---|---|---|---|---|
| % Embryos showing ectopic sox17 expression | 30 | 46 | 49 | 64 | 3 | 54 |
| Total number of embryos | 381 | 214 | 182 | 205 | 167 | 118 |