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Table 1.

Cdx2-/- blastocysts plated on different substrata fail to attach and form a trophoblast outgrowth

Cdx2genotype*
ECM substrate+/++/--/-
Fibronectin 43/43 75/75 0/29(1) 
Gelatin 5/5 10/10 0/4(1) 
Laminin 12/12 13/13 0/7 
No substrate 2/2 10/10 0/3 
Cdx2genotype*
ECM substrate+/++/--/-
Fibronectin 43/43 75/75 0/29(1) 
Gelatin 5/5 10/10 0/4(1) 
Laminin 12/12 13/13 0/7 
No substrate 2/2 10/10 0/3 

Blastocysts from Cdx2+/- heterozygous intercrosses were plated in serum-containing medium on uncoated tissue culture dishes or pre-coated with fibronectin, gelatin or laminin (see Materials and methods).

*

For each substrate and genotype, the number of formed outgrowths/plated embryos is indicated

None of the Cdx2-/- embryos formed an outgrowth; number in parentheses indicates number of embryos showing attached parietal endoderm cells

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