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Table 1.

Sequence similarity comparison between MEP50 and Drosophila WD domain proteins

Percentage identity with the regions of MEP50 indicated
WD domains separately
Gene/synonymPredicted or confirmed functionReferenceWhole alignmentWD domains combined123456
CG6486 Peroxisome organization and biogenesis FlyBase 23.2 26.9 15.6 30.3 29 21.9 31.2 33.3 
CG8440/Lis-1 Dynein-dependent microtubule transport Swan et al., 1999 20.2 26.7 27.3 38.7 25 12.5 37.5 19.2 
CG10728/vls Posterior development This paper 20.4 26.1 22.6 40.6 25.8 32.4 14.3 28 
CG4236/chromatin assembly factor 1 subunit (caf1) Histone lysine N-methylation Martinez-Balbas et al., 1998 21.8 25.7 18.8 25 29.7 24.2 34.4 22.2 
CG3000/retina aberrant in pattern (rap) Cyclin catabolism, proteolysis and peptidolysis Karpilow et al., 1989 18.3 24.9 27.3 28.1 34.4 11.4 21.2 26.9 
CG3436 Pre-mRNA splicing factor, component of snRNP U5 FlyBase 20.2 24.3 12.5 40.6 32.3 15.2 22.2 23.1 
Average   21.1 25.8 19.1 33.9 29.0 18.8 28.1 26.0 
Percentage identity with the regions of MEP50 indicated
WD domains separately
Gene/synonymPredicted or confirmed functionReferenceWhole alignmentWD domains combined123456
CG6486 Peroxisome organization and biogenesis FlyBase 23.2 26.9 15.6 30.3 29 21.9 31.2 33.3 
CG8440/Lis-1 Dynein-dependent microtubule transport Swan et al., 1999 20.2 26.7 27.3 38.7 25 12.5 37.5 19.2 
CG10728/vls Posterior development This paper 20.4 26.1 22.6 40.6 25.8 32.4 14.3 28 
CG4236/chromatin assembly factor 1 subunit (caf1) Histone lysine N-methylation Martinez-Balbas et al., 1998 21.8 25.7 18.8 25 29.7 24.2 34.4 22.2 
CG3000/retina aberrant in pattern (rap) Cyclin catabolism, proteolysis and peptidolysis Karpilow et al., 1989 18.3 24.9 27.3 28.1 34.4 11.4 21.2 26.9 
CG3436 Pre-mRNA splicing factor, component of snRNP U5 FlyBase 20.2 24.3 12.5 40.6 32.3 15.2 22.2 23.1 
Average   21.1 25.8 19.1 33.9 29.0 18.8 28.1 26.0 
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