Summary of RNA-I experiments
| Gene* . | Number of embryos injected . | Number with a specific defect† . | Injected animals completing development (%) . | Animals with a specific defect (%) . | Specific defect . | Wild-type function . |
|---|---|---|---|---|---|---|
| tiptop | 969 | 52 | 19.4 | 27.6 | Fusion of distal leg, distal leg to antenna | Segmentation and specification of distal leg |
| Antp | 418 | 64 | 39.7 | 38.5 | Fusion of medial and distal leg segments | Segmentation and specification of medial and distal leg |
| Dfd | 551 | 65 | 30.1 | 39.1 | Deformed maxilla, mandible to antenna | Specification of maxilla and mandible |
| Scr | 481 | 39 | 32.6 | 24.8 | Labium to antenna, loss of T1 leg comb | Specification of labium and leg comb |
| Ubx | 300 | 23 | 29.7 | 25.8 | Ectopic appendage and sternite in A1. A1 and T3 to T2 | Specification of A1 and T3 |
| Antp+tiptop | 718 | 49 | 26.7 | 25.5 | Fusion of medial and distal leg segments, leg to antenna | |
| Control | 975 | 0‡ | 42.5 | 0‡ |
| Gene* . | Number of embryos injected . | Number with a specific defect† . | Injected animals completing development (%) . | Animals with a specific defect (%) . | Specific defect . | Wild-type function . |
|---|---|---|---|---|---|---|
| tiptop | 969 | 52 | 19.4 | 27.6 | Fusion of distal leg, distal leg to antenna | Segmentation and specification of distal leg |
| Antp | 418 | 64 | 39.7 | 38.5 | Fusion of medial and distal leg segments | Segmentation and specification of medial and distal leg |
| Dfd | 551 | 65 | 30.1 | 39.1 | Deformed maxilla, mandible to antenna | Specification of maxilla and mandible |
| Scr | 481 | 39 | 32.6 | 24.8 | Labium to antenna, loss of T1 leg comb | Specification of labium and leg comb |
| Ubx | 300 | 23 | 29.7 | 25.8 | Ectopic appendage and sternite in A1. A1 and T3 to T2 | Specification of A1 and T3 |
| Antp+tiptop | 718 | 49 | 26.7 | 25.5 | Fusion of medial and distal leg segments, leg to antenna | |
| Control | 975 | 0‡ | 42.5 | 0‡ |
Control refers to embryos injected with buffer and mock transcription reactions.
T1, T2, T3: first, second and third thoracic segments.
A1: first abdominal segment.
Gene that corresponds to the dsRNA injected
Number of embryos that produced a repeatable defect not seen in control injections of buffer
By definition, defects seen in controls, usually deletions, are not considered to be specific defects.