The Company of Biologists

Table 1.

Allometric measurements

	Wild type	PAPPA^−/−	%	P value
Body weight (g)	33.7±1.5	18.0±0.9	53	<0.0001
Heart (g)	0.1760±0.0075	0.1070±0.0058	61	<0.0001
Spleen (g)	0.0930±0.0067	0.0400±0.0033	43	<0.0001
Liver (g)	1.674±0.093	0.922±0.084	55	<0.0001
Kidney (g)	0.208±0.008	0.121±0.009	58	<0.0001
Body length(mm)^{^*}	95.0±1.3	84.0±2.1	88	0.0012
Femur length (mm)	15.9±0.3	14.0±0.2	88	0.0004

	Wild type	PAPPA^−/−	%	P value
Body weight (g)	33.7±1.5	18.0±0.9	53	<0.0001
Heart (g)	0.1760±0.0075	0.1070±0.0058	61	<0.0001
Spleen (g)	0.0930±0.0067	0.0400±0.0033	43	<0.0001
Liver (g)	1.674±0.093	0.922±0.084	55	<0.0001
Kidney (g)	0.208±0.008	0.121±0.009	58	<0.0001
Body length(mm)^{^*}	95.0±1.3	84.0±2.1	88	0.0012
Femur length (mm)	15.9±0.3	14.0±0.2	88	0.0004

Body and tissue weights and lengths (mean±s.e.m.) of six wild-type and six PAPPA^−/− male mice at 8 weeks.

%, percent of PAPPA^−/− weight or length compared with wild-type weight or length.

Body length was measured as nose-to-anus.