The effect of mis-expression of wild-type and mutant Dup proteins
—, Wild-type nuclei; +, enlarged nuclei, >4C DNA content; ++, many enlarged nuclei, increased fraction >4C DNA content
—, Wild-type nuclei; +, pycnotic nuclei, Acridine Orange and activated caspase staining; ++, many pycnotic nuclei, Acridine Orange and activated caspase staining
+, Wild-type appearance of BrdU amplification foci; +++, increased;—, no BrdU
Sign In or Create an Account