The effect of FrdMO and DprMO on neural plate closure
| . | . | . | Phenotypes (%) . | . | |
|---|---|---|---|---|---|
| Experimental groups . | Dose/embryo . | n* . | Normal . | Open neural plate . | |
| Control MO | 8 ng | 45 | 93 | 7 | |
| FrdMO | 8 ng | 42 | 21 | 79 | |
| DprMO | 4 ng | 53 | 28 | 72 | |
| FrdMO+Frodo | 8 ng+1 ng | 40 | 62 | 38 | |
| FrdMO+βcat | 8 ng+10 pg | 42 | 7 | 93 | |
| . | . | . | Phenotypes (%) . | . | |
|---|---|---|---|---|---|
| Experimental groups . | Dose/embryo . | n* . | Normal . | Open neural plate . | |
| Control MO | 8 ng | 45 | 93 | 7 | |
| FrdMO | 8 ng | 42 | 21 | 79 | |
| DprMO | 4 ng | 53 | 28 | 72 | |
| FrdMO+Frodo | 8 ng+1 ng | 40 | 62 | 38 | |
| FrdMO+βcat | 8 ng+10 pg | 42 | 7 | 93 | |
Eight- to sixteen-cell stage embryos were injected with MOs and RNAs as indicated above into the right animal-dorsal blastomere. Phenotypes were scored morphologically at stages 18-20.
The data were obtained from two separate experiments.
Number of scored embryos