bapx1 is required for both arch one and arch two joints in moz mutants
| . | . | % lacking joints . | . | |
|---|---|---|---|---|
| . | Genotype . | Arch 1 . | Arch 2 . | |
| Control | Wild type | 0 (0/120) | 0 (0/120) | |
| moz- | 0 (0/42) | 4 (1.5/42) | ||
| bapx1-MO | Wild type | 89 (74/83) | 0 (0/83) | |
| moz- | 91 (24.5/27) | 70 (19/27)* | ||
| . | . | % lacking joints . | . | |
|---|---|---|---|---|
| . | Genotype . | Arch 1 . | Arch 2 . | |
| Control | Wild type | 0 (0/120) | 0 (0/120) | |
| moz- | 0 (0/42) | 4 (1.5/42) | ||
| bapx1-MO | Wild type | 89 (74/83) | 0 (0/83) | |
| moz- | 91 (24.5/27) | 70 (19/27)* | ||
Control uninjected animals and bapx1-MO injected animals were PCR genotyped, then assayed for skeletal morphology in cleared Alcian Green stained whole-mount preparations.
Significantly higher in moz mutants (P<0.001 by chi-square).