Mutant cells do not colonize the AER of chimeric limb buds
| . | Number of lacZ-positive cells/section (average) . | . | . | ||
|---|---|---|---|---|---|
| . | Surface ectoderm . | Limb ectoderm . | AER . | ||
| Wild-type | 24 | 7 | 4 | ||
| Fgfr2+/+↔Fgfr2+/+ | 20 | 5 | 3 | ||
| chimera | 37 | 8 | 4 | ||
| 42 (30.8) | 9 (7.25) | 5 (4.0) | |||
| Mutant | 12 | 3 | 0 | ||
| Fgfr2Δ2/Δ2↔Fgfr2+/+ | 10 | 3 | 0 | ||
| chimera | 20 | 1 | 0 | ||
| 18 | 3 | 0 | |||
| 16 | 4 | 0 | |||
| 24 | 1 | 0 | |||
| 29 | 2 | 0 | |||
| 28 | 2 | 0 | |||
| 30 | 5 | 1 | |||
| 16 (20.3) | 4 (2.8) | 0 (0.1) | |||
| . | Number of lacZ-positive cells/section (average) . | . | . | ||
|---|---|---|---|---|---|
| . | Surface ectoderm . | Limb ectoderm . | AER . | ||
| Wild-type | 24 | 7 | 4 | ||
| Fgfr2+/+↔Fgfr2+/+ | 20 | 5 | 3 | ||
| chimera | 37 | 8 | 4 | ||
| 42 (30.8) | 9 (7.25) | 5 (4.0) | |||
| Mutant | 12 | 3 | 0 | ||
| Fgfr2Δ2/Δ2↔Fgfr2+/+ | 10 | 3 | 0 | ||
| chimera | 20 | 1 | 0 | ||
| 18 | 3 | 0 | |||
| 16 | 4 | 0 | |||
| 24 | 1 | 0 | |||
| 29 | 2 | 0 | |||
| 28 | 2 | 0 | |||
| 30 | 5 | 1 | |||
| 16 (20.3) | 4 (2.8) | 0 (0.1) | |||
Each line represents one section. In each section allβ-galactosidase-positive cells were counted. The sections are consecutive 10 μm sections derived serial sectioning.