Table 3.

Dorsal injection of murine LPP3 induces a ventralizing phenotype in Xenopus embryos

Mouse LPP3 RNA (ng)Injection siteEmbryos injectedEmbryos with microcephalic phenotype%
0.4 Dorsal 40 20 50 
1.0 Dorsal 59 50 85 
1.0 Ventral 35 0 0 
2.5 Dorsal 49 49 100 
2.5 Ventral 29 5 17 
Mouse LPP3 RNA (ng)Injection siteEmbryos injectedEmbryos with microcephalic phenotype%
0.4 Dorsal 40 20 50 
1.0 Dorsal 59 50 85 
1.0 Ventral 35 0 0 
2.5 Dorsal 49 49 100 
2.5 Ventral 29 5 17 
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