Genotype . | E7.5 n(%) . | E8.5 n(%) . | E9.5 n(%) . | E10.5 n(%) . | Born n(%) . |
---|---|---|---|---|---|
Wild type | 11 (24) | 21 (23) | 24 (23) | 6 (20) | 72 (26) |
Heterozygous | 22 (48) | 55 (60) | 50 (48) | 14 (48) | 202 (74) |
Homozygous | 13 (28)* | 16 (17)* | 29 (28)* | 9 (31) | 0 (0) |
Genotype . | E7.5 n(%) . | E8.5 n(%) . | E9.5 n(%) . | E10.5 n(%) . | Born n(%) . |
---|---|---|---|---|---|
Wild type | 11 (24) | 21 (23) | 24 (23) | 6 (20) | 72 (26) |
Heterozygous | 22 (48) | 55 (60) | 50 (48) | 14 (48) | 202 (74) |
Homozygous | 13 (28)* | 16 (17)* | 29 (28)* | 9 (31) | 0 (0) |
Bold, embryos reaching these stages also lacked a chorio-allantoic placenta, with an abnormal allantois and were developmentally delayed.
31% of the embryos had axis duplication or were highly abnormal.