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Table 1.

Activation of EGL-30 promotes vulva development

Relevant genotype*%Muv%VulVPC induction§nPvalue**
Wild type 3.0±0.0 31  
egl-30(tg26gf) 3.0±0.0 20  
lin-3(n378) 96 0.7±1.0 51  
egl-30(tg26gf); lin-3(n378) 35 2.8±0.7 20 <0.0005 versus lin-3(n378) 
let-23(sy1) 100 0.5±0.9 24  
egl-30(tg26gf); let-23(sy1) 7.7 65 2.6±1.0 37 <0.0005 versus let-23(sy1) 
phm-2(ad538); let-23(sy1) 100 0.1±0.4 20 <0.0005 versus egl-30(tg26gf); let-23(sy1) 
goa-1(n363); let-23(sy1) 100 0.4±0.9 24 <0.0005 versus egl-30(tg26gf); let-23(sy1) 
egl-30(ad805); let-23(sy1) 94 0.6±1.0 52 0.65 versus let-23(sy1) 
egl-30(ad805); let-23(sy1); syEx532 [egl-30(+)XS] 3.6 71 1.9±1.2 56 0.004 versus egl-30(ad805); let-23(sy1) 
Relevant genotype*%Muv%VulVPC induction§nPvalue**
Wild type 3.0±0.0 31  
egl-30(tg26gf) 3.0±0.0 20  
lin-3(n378) 96 0.7±1.0 51  
egl-30(tg26gf); lin-3(n378) 35 2.8±0.7 20 <0.0005 versus lin-3(n378) 
let-23(sy1) 100 0.5±0.9 24  
egl-30(tg26gf); let-23(sy1) 7.7 65 2.6±1.0 37 <0.0005 versus let-23(sy1) 
phm-2(ad538); let-23(sy1) 100 0.1±0.4 20 <0.0005 versus egl-30(tg26gf); let-23(sy1) 
goa-1(n363); let-23(sy1) 100 0.4±0.9 24 <0.0005 versus egl-30(tg26gf); let-23(sy1) 
egl-30(ad805); let-23(sy1) 94 0.6±1.0 52 0.65 versus let-23(sy1) 
egl-30(ad805); let-23(sy1); syEx532 [egl-30(+)XS] 3.6 71 1.9±1.2 56 0.004 versus egl-30(ad805); let-23(sy1) 
*

In the egl-30(tg26gf); let-23(sy1) strain, let-23(sy1)was linked to unc-4(e120). syEx denotes a transgene. syEx532contains the wild-type egl-30 gene.

Multivulva. Percentage of animals that have greater than three VPCs induced.

Vulvaless. Percentage of animals that have less than three VPCs induced.

§

Average number of VPCs induced to vulval fates.

Number of animals assayed.

**

P values were calculated for VPC induction using Student's t-test.

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