Quantification of ureteric tips loss in Wnt11-/-kidneys
Number of ureteric tips
.
Wild type(%) (n=57)
.
Wnt11-/-(%) (n=11)
.
8
5
0
7
42
0
6
49
0
5
4
64
4
0
36
Number of ureteric tips
.
Wild type(%) (n=57)
.
Wnt11-/-(%) (n=11)
.
8
5
0
7
42
0
6
49
0
5
4
64
4
0
36
Ureteric tips from E12.5 wild-type and Wnt11-/- kidneys hybridized with Ret antisense probe were counted. The percentage of kidneys (n=57 for wild type, 11 for mutant) with eight, seven, six,five or four tips is shown. Wnt11-/- kidneys show a statistically significant (P<0.001) difference from wild-type frequencies for the distribution of ureteric tips.